FlyBase Allele Report: Dmel\iav[UAS.cKa]

General Information

Symbol

Dmel\iav^UAS.cKa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Kwon

FlyBase ID

FBal0246487

Feature type

allele

Associated gene

Dmel\iav

Associated Insertion(s)

Carried in Construct

P{UAS-iav.K}

Also Known As

UAS-iav

Key Links

Transgenic product class

cDNA

(Kwon et al., 2010)

wild_type

(Kwon et al., 2010)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Kwon et al., 2010)

wild_type

(Kwon et al., 2010)

Mutagen

in vitro construct

(Kwon et al., 2010)

Progenitor genotype

Carried in construct

P{UAS-iav.K}

Cytology

Description

UASt regulatory sequences drive expression of an iav cDNA.

(Kwon et al., 2010)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

iav

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | third instar larval stage, with Scer\GAL4^Toll-6-D42

(Wong et al., 2014)

abnormal neuroanatomy | third instar larval stage, with Scer\GAL4^VGlut1-OK371

(Wong et al., 2014)

abnormal neurophysiology | third instar larval stage, with Scer\GAL4^VGlut1-OK371

(Wong et al., 2014)

Phenotype Manifest In

embryonic/larval hypodermal muscle cell | third instar larval stage, with Scer\GAL4^Toll-6-D42

(Wong et al., 2014)

embryonic/larval hypodermal muscle cell | third instar larval stage, with Scer\GAL4^VGlut1-OK371

(Wong et al., 2014)

NMJ bouton | decreased number | third instar larval stage, with Scer\GAL4^Toll-6-D42

(Wong et al., 2014)

NMJ bouton | decreased number | third instar larval stage, with Scer\GAL4^VGlut1-OK371

(Wong et al., 2014)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

iav^UAS.cKa/Scer\GAL4^Toll-6-D42 rescues iav^hypoB-1

(Wong et al., 2014)

Scer\GAL4^VGlut1-OK371/iav^UAS.cKa rescues iav^hypoB-1

(Wong et al., 2014)

Scer\GAL4^iav.PK/iav^UAS.cKa rescues iav^hypoB-1

(Kwon et al., 2010)

iav^UAS.cKa/Scer\GAL4^pain-GAL4 rescues iav^hypoB-1

(Kwon et al., 2010)

Scer\GAL4^nan.PK/iav^UAS.cKa rescues iav^hypoB-1

(Kwon et al., 2010)

Fails to rescue

iav^UAS.cKa/Scer\GAL4^ato.3.6 fails to rescue iav^hypoB-1

(Wong et al., 2014)

Scer\GAL4^Mef2.PR/iav^UAS.cKa fails to rescue iav^hypoB-1

(Wong et al., 2014)

Comments

Expression of iav^Scer\UAS.cKa under the control of one of Scer\GAL4^iav.PK, Scer\GAL4^pain-GAL4 or Scer\GAL4^nan.PK rescues the deficit in cool temperature discrimination (distinguishing between 17.5[o] and 14[o]C) of iav^hypoB-1 larvae.

(Kwon et al., 2010)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

iav^Scer\UAS.cKa

iav^UAS.cKa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Kwon

Secondary FlyBase IDs

References (5)

Report Sections

Open Close