FlyBase Allele Report: Dmel\dlp[HMS00903]

General Information

Symbol

Dmel\dlp^HMS00903

Species

D. melanogaster

Name

FlyBase ID

FBal0257578

Feature type

allele

Associated gene

Dmel\dlp

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS00903}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS00903}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS00903

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates atypical teratoid rhabdoid tumor

modeled by Snr1^KK101602

(Tegeder et al., 2019)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell adhesion | oogenesis, with Scer\GAL4^slbo.2.6

(Raza et al., 2019)

abnormal cell migration | oogenesis, with Scer\GAL4^slbo.2.6

(Raza et al., 2019)

decreased size | adult stage, with Scer\GAL4^Ser.PGF

(Zaytseva et al., 2023)

Phenotype Manifest In

border follicle cell, with Scer\GAL4^slbo.2.6

(Raza et al., 2019)

wing posterior compartment, with Scer\GAL4^Ser.PGF

(Zaytseva et al., 2023)

Detailed Description

Statement

Reference

The expression of dlp^HMS00903 under the control of Scer\GAL4^slbo.2.6 leads to some border cell cluster disassociation events, and leads to prevalent border cell migration failure or delay.

(Raza et al., 2019)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

dlp^HMS00903, Scer\GAL4^Ser.PGF is a suppressor of decreased size | adult stage phenotype of Psi^KK101882, Scer\GAL4^Ser.PGF

(Zaytseva et al., 2023)

Scer\GAL4^repo.PU/dlp^HMS00903 is a suppressor | partially of lethal - all die during P-stage phenotype of Scer\GAL4^repo.PU, brm^GD4507

(Tegeder et al., 2019)

Scer\GAL4^repo.PU/dlp^HMS00903 is a suppressor | partially of lethal - all die during P-stage phenotype of Scer\GAL4^repo.PU, Snr1^KK101602

(Tegeder et al., 2019)

Other

Statement

Reference

Scer\GAL4^repo.PU, brm^GD4507, dlp^HMS00903 has partially lethal - majority die phenotype

(Tegeder et al., 2019)

Scer\GAL4^repo.PU, Snr1^KK101602, dlp^HMS00903 has partially lethal - majority die phenotype

(Tegeder et al., 2019)

Phenotype Manifest In

Suppressor of

Statement

Reference

dlp^HMS00903, Scer\GAL4^Ser.PGF is a suppressor of wing posterior compartment phenotype of Psi^KK101882, Scer\GAL4^Ser.PGF

(Zaytseva et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

NIG-Fly

HMS00903

y¹ sc^* v¹ sev²¹; P{TRiP.HMS00903}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

dlp^HMS00903

dlp^RNAi

(Ma et al., 2019)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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