FB2025_01 , released February 20, 2025
Allele: Dmel\Mpc1UAS.cBa
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General Information
Symbol
Dmel\Mpc1UAS.cBa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Bricker
FlyBase ID
FBal0276931
Feature type
allele
Associated gene
Dmel\Mpc1
Associated Insertion(s)
Carried in Construct
P{UAS-Mpc1.B}
Key Links
Transgenic product class
wild_type
(Bricker et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Bricker et al., 2012)
Mutagen
in vitro construct
(Bricker et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-Mpc1.B}
Cytology
Description

UAS regulatory sequences drive expression of Mpc1.

(Bricker et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Mpc1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4Tub.PU/Mpc1UAS.cBa rescues Mpc12/Mpc11

      (Bricker et al., 2012)

      Scer\GAL4Cg.PA/Mpc1UAS.cBa rescues Mpc12/Mpc11

      (Bricker et al., 2012)

      Scer\GAL4Mef2.PR/Mpc1UAS.cBa rescues Mpc12/Mpc11

      (Bricker et al., 2012)

      Mpc1UAS.cBa/Scer\GAL4elav.PLu rescues Mpc12/Mpc11

      (Bricker et al., 2012)
      Fails to rescue

      Scer\GAL4mex1.2.1/Mpc1UAS.cBa fails to rescue Mpc12/Mpc11

      (Bricker et al., 2012)
      Comments

      Expression of Mpc1Scer\UAS.cBa under the control of Scer\GAL4tub.PU rescues the lethality seen in Mpc11/Mpc12 mutant flies on a sucrose diet. The lethality is also rescued when Mpc1Scer\UAS.cBa is expressed in the fat body (Scer\GAL4Cg.PA), muscle (Scer\GAL4Mef2.PR) or neurons (Scer\GAL4elav.PLu). No rescue is seen when Mpc1Scer\UAS.cBa is expressed in the gut under the control of Scer\GAL4mex1.2.1.

      (Bricker et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Mpc1Scer\UAS.cBa
      Mpc1UAS.cBa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Bricker
      Secondary FlyBase IDs
        References (1)