FB2025_01 , released February 20, 2025
Gene Group: HISTONE DEMETHYLASES
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General Information
Name
HISTONE DEMETHYLASES
Species
D. melanogaster
Symbol
KDM
FlyBase ID
FBgg0000307
Date last reviewed
2021-07-12
Number of members
11
Description
Description
Histone demethylases mediate the removal of methyl groups from lysine or arginine residues of histones. (Adapted from FBrf0218651.)
Notes on Group
Source Material
The HISTONE DEMETHYLASES Gene Group has been compiled using the following publication(s): Shalaby et al., 2017, Holowatyj et al., 2015, Greer and Shi, 2012, Rudolph et al., 2007, and Klose et al., 2006 .
Key Gene Ontology (GO) terms
Molecular Function
histone demethylase activity
Biological Process
post-translational protein modification
Cellular Component
nucleus
Related Gene Groups
Parent group(s)
OXIDOREDUCTASES
Component group(s)
JMJC FAMILY HISTONE DEMETHYLASES
LSD1 FAMILY HISTONE DEMETHYLASES
Members (11)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
JMJC FAMILY HISTONE DEMETHYLASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG10600
(FlyBase, 2017-)
JMJD5
Jumonji domain containing 5
(Shalaby et al., 2017, Holowatyj et al., 2015, Klose et al., 2006)
JMJD6
Jumonji domain containing 6
PSR, dPSR, phosphatidylserine receptor
(Shalaby et al., 2017, Holowatyj et al., 2015, Klose et al., 2006)
Kdm2
Lysine demethylase 2
dKDM2, JHDM1, Lysine (K)-specific demethylase 2
(Shalaby et al., 2017, Holowatyj et al., 2015, Klose et al., 2006)
Kdm3
Lysine demethylase 3
JHDM2
(Shalaby et al., 2017, Holowatyj et al., 2015, Klose et al., 2006)
Kdm4A
Lysine demethylase 4A
dKDM4A, Histone demethylase 4A
(Shalaby et al., 2017, Holowatyj et al., 2015, Greer and Shi, 2012, Klose et al., 2006)
Kdm4B
Lysine demethylase 4B
Histone demethylase 4B
(Shalaby et al., 2017, Holowatyj et al., 2015, Greer and Shi, 2012, Klose et al., 2006)
Kdm5
Lysine demethylase 5
lid, little imaginal discs, l(2)10424, dKDM5/LID
(Shalaby et al., 2017, Holowatyj et al., 2015, Greer and Shi, 2012, Klose et al., 2006)
NO66
Nucleolar protein 66
anon-4Bd
(Shalaby et al., 2017, Holowatyj et al., 2015, Klose et al., 2006)
Utx
Utx histone demethylase
dUTX, anon-31BCa
(Shalaby et al., 2017, Holowatyj et al., 2015, Klose et al., 2006)
LSD1 FAMILY HISTONE DEMETHYLASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Su(var)3-3
Suppressor of variegation 3-3
dLsd1, Lsd1, Suvar(3)3, Su-var(3)3, Histone demethylase
(Holowatyj et al., 2015, Greer and Shi, 2012, Rudolph et al., 2007)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
KDM
K(lysine) demethylases
Histone demethylases
HDM
LYSINE DEMETHYLASES
HISTONE LYSINE DEMETHYLASES
HISTONE DEMETHYLASES
Secondary FlyBase ID(s)
References (7)