FB2026_03 , released September 17, 2026
Aberration: Dmel\T(2;3)apXa
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General Information
Symbol
T(2;3)apXa
Species
D. melanogaster
Name
Translocation (2;3) apterous-Xasta
FlyBase ID
FBab0007867
Feature type
chromosomal_translocation
Computed Cytological Breakpoints (relative to progenitor)

41F9-41F11;89E8-89F1

Sequenced Breakpoints (relative to progenitor)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order

2Lt - 41F | 89E8 - 89C3 | 96A19 - 3Rt ; 2Rt - 58B1 | 42A3 - 58A4 | 42A2 - 41F | 89F1 - 96A18 | 89C2 - 3Lt

(Lewis, 1951)
Progenitor
In(2R)Cy
In(3R)P
Mutagen
X ray
Class of aberration (relative to wild type)
chromosomal_translocation
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_translocation
Cytological Breakpoints (relative to progenitor)
Causes alleles
apXa
(Bieli et al., 2015, Jack and DeLotto, 1992, Sturtevant, 1934)
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 hits ap

Genetic mapping information
Comments

A reciprocal translocation involving the right arms of the second and third chromosomes causes a breakpoint just upstream of the ap-RXa wing enhancer that juxtaposes the Dad and ap loci. The coordinates of the breakpoints are: 2R:5375319 and 3R:17065902 (FlyBase Release FB2014_06).

(Bieli et al., 2015)
Comments on Cytology

Cytology by FBrf0064033 corrected by FBrf0008101.

(Lewis, 1951)

Limits of break 1 from complementation mapping against ap (citation unavailable) Limits of break 2 from polytene analysis (citation unavailable)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
ap
(Bieli et al., 2015)
Dad
(Bieli et al., 2015)
Genes NOT Deleted / Disrupted
Complementation Data
 
DNaseII
(Evans et al., 2002)
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    The 41F breakpoint ( 2R:5375319 ) is just upstream of the "ap-RXa" wing enhancer resulting in dominant ap phenotypes (FBrf0228676).

    (Parks and Cook, 2026.8.6)

    Homozygote virtually lethal.

    Stocks (42)
    Notes on Origin
    Discoverer

    Serebrovsky, Jan. 1928.

     

    X-rays were used to induce a reciprocal translocation (41F;89E8-F1) between In(2R)Cy (42A2-3;58A4) and In(3R)P (89C2-3;96A18-19).

    (Parks and Cook, 2026.8.6)
    Balancer / Genotype Variants of the Aberration
    Separable Components
     
    Other Comments
     

    Effective as a balancer for medial regions of 2R and 3R, but it does not effectively balance 2L, 3L or the distal ends of 2R and 3R.

    (Parks and Cook, 2026.8.6)

    The first X-ray-induced mutation recovered in the USSR.

    Synonyms and Secondary IDs (9)
    Reported As
    Symbol Synonym
    T(2;3)ApXa
    (Bornemann et al., 1996)
    T(2;3)Xa
    (Burdick, 1999)
    T(2;3)ap-Xa
    T(2;3)apXa
    (Parks and Cook, 2026.8.6, Vernizzi and Lehner, 2022, Bieli et al., 2015)
    T(2;3)apXa
    (Bejarano and Busturia, 2004)
    Xa
    (Hetherington et al., 1968)
    Name Synonyms
    Translocation (2;3) apterous-Xasta
    Translocation(2;3)Xasta
    Xasta
    (Hetherington et al., 1968)
    Secondary FlyBase IDs
      References (19)