Homozygous lethal. Lethality is rescued by egh+t7, rescued adults are female sterile (exhibit a maternal effect lethal egg phenotype) and male semisterile. Females lay eggs that are fertilised with sperm but the large majority arrest prior to completion of the first embryonic mitotic division. More than 50% males are completely sterile, the remainder produce a small number of progeny. In male testes a high proportion of postmeiotic spermatids show obvious aberrations (abnormally large Nebenkern) as a result of defects in cytokinesis due to disruption of the central spindle during the meiotic divisions.
