FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2R)ED2308
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General Information
Symbol
Df(2R)ED2308
Species
D. melanogaster
Name
FlyBase ID
FBab0033603
Feature type
chromosomal_deletion
Also Known As
ED2308
Computed Breakpoints include

[49C3-49C3];[49E7-49E7];

Features within 49C3--49E7
Genomic Maps
Sequence coordinates
2R:12,780,370..12,780,370 (Df(2R)ED2308:bk1)
(DrosDel Project, 2007.6.25)
2R:12,996,984..12,996,984 (Df(2R)ED2308:bk2)
(DrosDel Project, 2007.6.25)
Member of large scale dataset(s)
Dfs_DrosDel_set1

A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial core set of 209 isogenic deletions provides ~60% euchromatic genome coverage.

(Ryder et al., 2007)
Nature of Aberration
Cytological Order
Progenitor
P{RS3r}CB-0427-3
(Ryder and Roote, 2005.11.4)
P{RS5r}5-SZ-3055
(Ryder and Roote, 2005.11.4)
Mutagen
FLPase
(Ryder and Roote, 2005.11.4)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Ryder and Roote, 2005.11.4, Ryder, 2003.6.17)
Breakpoints

49C3;49E7

(FlyBase Curators, 2008)
Causes alleles
Carries alleles
Transposon Insertions
P{3'.RS5+3.3'}ED2308
(Ryder and Roote, 2005.11.4)
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology

Confirmed by 3-step PCR confirmation as shown in http://www.drosdel.org.uk/del_confirm.php Confirmed by lack of complementation to a known lethal mutation predicted to fall between the progenitor insertions.

(Ryder and Roote, 2005.11.4)

Limits of break 1 computationally determined from location of progenitor P insertion on genome sequence between P{PZ}Nacα04329 and P{lacW}bick10712 Limits of break 2 computationally determined from location of progenitor P insertion on genome sequence between P{lacW}Psck07834&P{lacW}Su(z)2k06344 and P{EP}EP873EP873

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
l(2)k09328
(Kahsai et al., 2016)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Nacα
(Yamada et al., 2023)
sie
(Kahsai and Cook, 2018)
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (40)
Phenotypic Data
In combination with other aberrations

Lethal in combination with Df(2R)Exel8056.

(Kahsai et al., 2016)
NOT in combination with other aberrations

Heterozygotes show hypersensitivity to halothane and enflurane compared to controls.

(Alone et al., 2009)
Stocks (2)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (3)
References (14)