[30B10-30B10];[30C1-30C1];
A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial set of 519 isogenic deletions provides 56% genome coverage.
The current Exelixis collection at the Bloomington Stock Center differs from the original described in FBrf0175003 : a significant number were shown not to carry a deletion and have been removed from the collection; a number of stocks have been lost; a number of additional deletions are included that were generated after publication.
30B10;30C1
Breakpoint based on release 3 sequence coordinate from Parks et al., 2004 (FBrf0174230), converted to release 5 coordinate.
Df(2L)Exel7042/Df(2L)200 embryos display intersegmental nerve b (ISNb) defects.
Increased apoptosis is seen in Df(2L)Exel7042 mutant embryos compared to controls.
Homozygous Df(2L)Exel7042 mutant embryos have an intersegmental nerve b (ISNb) phenotype that is a mixture of stall, bypass, and absence, in which there is no ISNb at all.
