FB2026_02 , released June 18, 2026
Aberration: Dmel\Df(3R)j3B9-rv12
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General Information
Symbol
Df(3R)j3B9-rv12
Species
D. melanogaster
Name
FlyBase ID
FBab0046716
Feature type
chromosomal_deletion
Computed Breakpoints include
Features within 100B2--100B2
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
P{lacW}dcoj3B9
(Nanda et al., 2009)
dcoj3B9
(Loh, 1999)
Mutagen
Delta2-3 transposase
(Nanda et al., 2009, Loh, 1999)
Class of aberration (relative to wild type)
chromosomal_deletion
(Nanda et al., 2009, FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Nanda et al., 2009, Loh, 1999)
Breakpoints

[];[]

(Loh, 1999)
Causes alleles
Sox100Bj3B9-rv12
(Loh, 1999)
dcoj3B9-rv12
(Nanda et al., 2009)
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

Imprecise excision of the progenitor insertion, resulting in a deletion that removes part of the dco gene and all of the Sox100B gene.

(Nanda et al., 2009)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
dco
(Loh, 1999)
Sox100B
(Nanda et al., 2009, Loh, 1999)
Partially deleted
dco
(Nanda et al., 2009)
Sox100B
(DeFalco et al., 2003)
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
CG11317
(Nanda et al., 2009)
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations

    Embryonic lethal in combination with Df(3R)tll-e.

    (Nanda et al., 2009)

    Inferred to overlap with: Df(3R)tll-e.

    (Nanda et al., 2009)

    Df(3R)j3B9-rv12 is lethal in combination with Df(3R)tll-e.

    (Loh, 1999)
    NOT in combination with other aberrations

    Homozygous embryonic lethal.

    Df(3R)j3B9-rv12/Df(3R)tll-e flies in which dco function has been rescued using dco+t13.1 survive to the pharate adult stage or die shortly after eclosing from the pupal case. The testes are severely reduced or absent in males of this genotype. The seminal vesicle is unpigmented in the mutant males. Some germ cells are present, but they are often aberrantly located. Occasional males develop partial testis lobes, but in no case is a normal coiled testis seen. All stages of spermatogenesis are observed in partially developed testes, and in these cases the muscle sheath is comparatively normal. Mutant larvae do not show defects in spermatogenesis, with wild-type cysts being observed in mutant testes, which are of similar size to the wild type. The mutants fail to show any sign of testis elongation during metamorphosis.

    The fat body is abnormal in Df(3R)j3B9-rv12/Df(3R)tll-e male and female flies in which dco function has been rescued using dco+t13.1 and it appears as though the larval fat body has not undergone its normal histolysis.

    The ovaries are relatively normal in female Df(3R)j3B9-rv12/Df(3R)tll-e pharate adults in which dco function has been rescued using dco+t13.1.

    (Nanda et al., 2009)

    In Df(3R)j3B9-rv12 mutants, the male-specific somatic gonadal precursors are able to form.

    (DeFalco et al., 2003)

    Homozygotes are lethal and appear to die at the first larval instar.

    (Loh, 1999)
    Stocks (0)
    Notes on Origin
    Discoverer

    S.H.Y. Loh

    (Loh, 1999)
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    A P-element insertion is still present on the chromosome.

    (Loh, 1999)
    Synonyms and Secondary IDs (5)
    Reported As
    Symbol Synonym
    12-78.2
    (Loh, 1999)
    Df(3R)Sox100B12-78.2
    Df(3R)j3B9-rv12
    J3B9RV12
    (DeFalco et al., 2003)
    j3B9-rv12
    (Nanda et al., 2009)
    Name Synonyms
    Secondary FlyBase IDs
    • FBab0045938
    • FBab0044726
    References (5)