FB2026_03 , released September 17, 2026
Aberration: Dmel\Df(2L)let-7-CKO2
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General Information
Symbol
Df(2L)let-7-CKO2
Species
D. melanogaster
Name
FlyBase ID
FBab0047615
Feature type
chromosomal_deletion
Also Known As
let-7-CKO2
Computed Cytological Breakpoints (relative to progenitor)
Sequenced Breakpoints (relative to progenitor)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
FLPase
(Wu et al., 2012)
I-SceI
(Wu et al., 2012)
ends-out gene targeting
(Wu et al., 2012)
Class of aberration (relative to wild type)
chromosomal_deletion
(Wu et al., 2012)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Wu et al., 2012)
Cytological Breakpoints (relative to progenitor)
Causes alleles
lncRNA:let7CKO2
(Wu et al., 2012)
Carries alleles
Transposon Insertions
TI{TI}lncRNA:let7CKO2
(Wu et al., 2012)
Formalized genetic data
Genetic mapping information
Comments

The endogenous let-7-C locus is replaced with w, resulting in deletion of mir-100, let-7 and mir-125.

(Wu et al., 2012)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
mir-100
(Wu et al., 2012)
mir-125
(Wu et al., 2012)
mir-let7
(Wu et al., 2012)
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    The number of Dl-positive intestinal stem cells per clone and the total number of cells per clone in MARCM clones in the homozygous Df(2L)let-7-CKO2 adult posterior midgut is not significantly different from that of controls.

    (Chen et al., 2015)
    Stocks (3)
    Notes on Origin
    Discoverer
     

    Generated in parallel with Df(2L)let-7-CGKI and is identical to it except that the endogenous let-7-C locus is replaced with w rather than w and Scer\GAL4.

    (Wu et al., 2012)
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Df(2L)let-7-CKO2
    let-7-CKO2
    (Wu et al., 2020, Chawla et al., 2016, Chen et al., 2015, Wu et al., 2012)
    Name Synonyms
    Secondary FlyBase IDs
      References (4)