FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2L)mir-275-305-KO
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General Information
Symbol
Df(2L)mir-275-305-KO
Species
D. melanogaster
Name
FlyBase ID
FBab0047657
Feature type
chromosomal_deletion
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
ends-out gene targeting
(Chen et al., 2014)
FLPase
(Chen et al., 2014)
I-SceI
(Chen et al., 2014)
Class of aberration (relative to wild type)
chromosomal_deletion
(Chen et al., 2014)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Chen et al., 2014)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
TI{TI}mir-275-305-KO
(Chen et al., 2014)
Formalized genetic data
Genetic mapping information
Comments

Deletion which removes the miRNA cluster containing the mir-275 and mir-305 miRNAs. A loxP cassette containing the w+mW.hs marker is present at the site of the deletion.

(Chen et al., 2014)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
mir-275
(Chen et al., 2014)
mir-305
(Chen et al., 2014)
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    Df(2L)mir-275-305-KO/Df(2L)BSC189 animals show partial lethality. Partial lethality due to a maternal effect is seen at the embryonic stage. Some lethality is seen during the larval stage.

    (Chen et al., 2014)

    Df(2L)mir-275-305-KO/Df(2L)BSC189 males and females have low fertility.

    (Chen et al., 2014)

    Df(2L)mir-275-305-KO/Df(2L)BSC189 males show a significant decrease in median lifespan compared to controls.

    (Chen et al., 2014)
    NOT in combination with other aberrations

    Homozygotes show partial lethality. Some lethality is seen during the embryonic stage and some during the larval stage.

    Homozygous males show a significant decrease in median lifespan compared to controls.

    Homozygous males and females have low fertility.

    (Chen et al., 2014)
    Stocks (1)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    Df(2L)mir-275-305-KO
    Name Synonyms
    Secondary FlyBase IDs
      References (2)