FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Dll15
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General Information
Symbol
Dmel\Dll15
Species
D. melanogaster
Name
FlyBase ID
FBal0001012
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
DllJ
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Progenitor genotype
Caused by aberration
Cytology
Description

Breakpoint mapped to within a 1.7kb EcoRI fragment spanning from approximately 2 to 4kb 3' to the transcription unit.

break at about 105 kb; 3' to putative coding region. Coordinates estimated from Cohen, Broenner, Kuettner, Jurgens and Jaeckle (1989); origin undefined; positive values extend to left.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Dll15/Dll17 animals have legs with deformed femurs and truncation of all tissues from the tibia onwards (distally).

Stage 12 homozygous embryos show normal or near normal pattern of transcripts in the ventral maxillary domain.

Heterozygotes show a transformation of antenna to leg. Homozygous and hemizygous embryos lack the H piece, labial sense organ, antennal sense organ, maxillary sense organ and Keilin's organs.

Differs from other tested alleles in being embryonic rather than pupal lethal in combination with Dll3 and Dll9.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Jurgens.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (6)