FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\bcd7
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General Information
Symbol
Dmel\bcd7
Species
D. melanogaster
Name
FlyBase ID
FBal0001081
Feature type
allele
Associated gene
Dmel\bcd
Associated Insertion(s)
Carried in Construct
Also Known As
bcdE2
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Berleth et al., 1988, Driever and Nusslein-Volhard, 1988, Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description

Homeodomain deleted.

(Rivera-Pomar et al., 1996)

Small deletion of 260bp within the bcd homeobox domain.

(Berleth et al., 1988)

Small deletion within the bcd coding region.

(Driever and Nusslein-Volhard, 1988)

260 base-pair deletion overlapping homeodomain

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:6,757,405..6,758,550 [-]
Linked to:
HindIII-HindIII restriction fragment
Comment:

Approximate location of bcd7 deletion. bcd7 is a small deletion of approximately 260bp. The 3' end of deletion was determined by SI nuclease mapping. The size of the deletion was determined by genomic southern analysis of HindIII digests.

(Berleth et al., 1988)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos derived from bcd6/bcd7 females show some development of at least thoracic and frequently head structures when injected at the anterior tip with cytoplasm taken from the anterior tip of wild-type embryos.

      (Frohnhofer and Nusslein-Volhard, 1987)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Statement
      Reference

      Tlr4, bcd7, cic1, osk6, tsl1 has embryo phenotype

      (Soluri et al., 2020)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      In contrast, cytoplasm taken from the anterior tip of embryos derived from exu1/exu2 females shows barely detectable rescuing activity when injected into the anterior tip of embryos derived from bcd6/bcd7 females. Cytoplasm taken from the anterior tip of embryos derived from swa1/swa2 females also shows reduced rescuing activity compared to wild-type cytoplasm when injected into the anterior tip of embryos derived from bcd6/bcd7 females. exu1 does not alter the phenotype of embryos derived from bcd6/bcd7 females.

      (Driever, 1993)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (3)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Strong bcd allele.

      (Driever and Nusslein-Volhard, 1988)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      References (11)