FB2026_02 , released June 18, 2026
Allele: Dmel\brm5
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General Information
Symbol
Dmel\brm5
Species
D. melanogaster
Name
FlyBase ID
FBal0001299
Feature type
allele
Associated gene
Dmel\brm
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Gindhart and Kaufman, 1995)
Mutagen
gamma ray
(Kennison and Tamkun, 1988)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Majority of lethality is observed during embryogenesis. There are no major abnormalities in formation or identity of the trunk segments. Formation of larval head structures is abnormal but the nature of the defects is undetermined.

      (Brizuela et al., 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      brm5 is a suppressor of phenotype of Pc4

      (Kennison and Tamkun, 1988)
      Other
      Statement
      Reference

      ash11, brm5/brm[+] has metathoracic leg phenotype

      (Tripoulas et al., 1994)

      ash128, brm5/brm[+] has metathoracic leg phenotype

      (Tripoulas et al., 1994)

      ash16, brm5/brm[+] has metathoracic leg phenotype

      (Tripoulas et al., 1994)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Suppresses the extra sex comb phenotype of Pc4, Ts(YLt;2Lt)L124. Causes between 50% and 100% suppression of the Pc4/+ extra sex combs phenotype.

      (Kennison and Tamkun, 1988)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      brm5
      (Di Stefano et al., 2011, Chang et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)