FlyBase Allele Report: Dmel\Delta[7]

General Information

Symbol

Dmel\Delta⁷

Species

D. melanogaster

Name

FlyBase ID

FBal0002467

Feature type

allele

Associated gene

Dmel\Delta

Associated Insertion(s)

Carried in Construct

Also Known As

Dl⁷

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell number | embryonic stage

(Pérez et al., 2022)

visible | dominant

(Domanitskaya and Schüpbach, 2012, Guo et al., 1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

Dl⁷ heterozygotes exhibit thickened veins and delta-like wing venation patterns.

(Kandasamy et al., 2021)

Dl⁷/+ wings exhibit mild deltas and thickening of L2 wing veins.

(van de Hoef et al., 2013)

The wings of heterozygous adults have thickened wing veins and small deltas located near the crossveins.

(Domanitskaya and Schüpbach, 2012)

Wing veins form deltas at their junctions.

(Guo et al., 1999)

The duplication of bristles seen at a low level in heterozygotes is enhanced in combination with RpII215^K2, RpII215^H1, RpII215⁷, RpII215⁴ or RpII215^Ubl.

(Mortin et al., 1988)

Like Dl⁵. RK3.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Delta⁷ has visible | dominant phenotype, enhanceable by CoRest[+]/CoRest^GF60

(Domanitskaya and Schüpbach, 2012)

Enhancer of

Statement

Reference

Delta⁷/Dl[+] is an enhancer of abnormal planar polarity phenotype of Scer\GAL4^hs.2sev, dgo^UAS.cFa

(Weber et al., 2012)

Delta⁷ is an enhancer of visible phenotype of Myt1^GMR.PP

(Price et al., 2002)

Delta⁷ is an enhancer of visible phenotype of Nsf2^EQ.UAS, Scer\GAL4^bbg-C96

(Stewart et al., 2001)

Phenotype Manifest In

Enhanced by

Statement

Reference

Delta⁷ has wing vein phenotype, enhanceable by Yif1^doc-1/Yif1[+]

(Kandasamy et al., 2021)

Delta⁷ has wing vein phenotype, enhanceable by Yif1^doc-16/Yif1[+]

(Kandasamy et al., 2021)

Delta⁷ has wing vein phenotype, enhanceable by Yif1^doc-99/Yif1[+]

(Kandasamy et al., 2021)

Delta⁷ has wing vein L2 phenotype, enhanceable by Fkbp14^D58/Fkbp14[+]

(van de Hoef et al., 2013)

Delta⁷ has wing vein | ectopic phenotype, enhanceable by Fkbp14^D58/Fkbp14[+]

(van de Hoef et al., 2013)

Delta⁷ has wing vein L2 phenotype, enhanceable by Psn[+]/Psn^W6

(van de Hoef et al., 2013)

Delta⁷ has wing vein | ectopic phenotype, enhanceable by Psn[+]/Psn^W6

(van de Hoef et al., 2013)

Delta⁷ has wing vein phenotype, enhanceable by CoRest[+]/CoRest^GF60

(Domanitskaya and Schüpbach, 2012)

Delta⁷ has wing vein phenotype, enhanceable by Psn^W11/Psn[+]

(Guo et al., 1999)

Delta⁷ has wing vein phenotype, enhanceable by Psn[+]/Psn^W6

(Guo et al., 1999)

NOT Enhanced by

Statement

Reference

Delta⁷ has wing vein L2 phenotype, non-enhanceable by Fkbp14[+]/Fkbp14^D34

(van de Hoef et al., 2013)

Delta⁷ has wing vein | ectopic phenotype, non-enhanceable by Fkbp14[+]/Fkbp14^D34

(van de Hoef et al., 2013)

Enhancer of

Statement

Reference

Delta⁷/Dl[+] is an enhancer of ommatidium phenotype of Scer\GAL4^hs.2sev, dgo^UAS.cFa

(Weber et al., 2012)

Delta⁷ is an enhancer of eye phenotype of Myt1^GMR.PP

(Price et al., 2002)

Delta⁷ is an enhancer of wing margin phenotype of Nsf2^EQ.UAS, Scer\GAL4^bbg-C96

(Stewart et al., 2001)

NOT Enhancer of

Statement

Reference

Delta⁷/Dl[+] is a non-enhancer of wing hair phenotype of Scer\GAL4^hs.2sev, dgo^UAS.cFa

(Weber et al., 2012)

NOT Suppressor of

Statement

Reference

Delta⁷/Dl[+] is a non-suppressor of wing hair phenotype of Scer\GAL4^hs.2sev, dgo^UAS.cFa

(Weber et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

Fkbp14^D58/+ and Psn^W6/+, but not Fkbp14^D34/+, enhance the L2 vein thickening and ectopic deltas seen in Dl⁷/+ wings.

(van de Hoef et al., 2013)

The wing defects seen in Dl⁷/+ flies are enhanced by CoRest^GF60/+: the extent of thickening and deltas at the wing veins is increased and in some cases severe wing blistering is seen.

(Domanitskaya and Schüpbach, 2012)

Dl⁷/+ enhances the ommatidial rotation defects induced by the overexpression of dgo^Scer\UAS.cFa under the control of Scer\GAL4^hs.2sev.

(Weber et al., 2012)

In double heterozygotes for Psn^W6 or Psn^W11 the wing vein deltas seen in Dl⁷ heterozygotes become more pronounced.

(Guo et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (1)

Holtzman, S. and Kaufman, T. (2013)

Mutant

Wild-type

Stocks (2)

485

105936

Notes on Origin

Discoverer

Schultz, 7th Jan. 1933.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Delta⁷

Df(3R)Dl⁷

(Weber et al., 2012)

Dl⁷

(Dutta et al., 2021, Kandasamy et al., 2021, van de Hoef et al., 2013, Domanitskaya and Schüpbach, 2012, Weber et al., 2012, Babaoglan et al., 2009)

delta⁷

(Pérez et al., 2022)

Name Synonyms

Secondary FlyBase IDs

References (15)

Report Sections

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