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General Information
Symbol
Dmel\esg35Ce-1
Species
D. melanogaster
Name
FlyBase ID
FBal0003842
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

esg05729/esg35Ce-1 pharate pupae have well-differentiated testes. The stem cells and spermatogenic cells that are normally found at the tip of the testis are missing in the mutants, with the mutant testes containing only sperm bundles and motile sperm.

The dorsal branch fusion cells form discrete branches that never meet or join. These cells go on to form additional branches that resemble normal terminal branches in the larva. Lateral trunk fusion branches are completely missing leaving a gap in each segment of the lateral trunk.

Many heteroallelic combinations studied. Where flies die as pharate adults sternite/tergites partially or completely deleted and/or legs are twisted. Where flies are viable, they have held out wings, and may have twisted legs, sternite/tergites partially deleted and be sickly. Abdominal histoblasts examined in heteroallelic combinations and found to have nuclei 3.4 fold times larger (revealed by Ecol\lacZ expression from esg05729 allele) and with 7-16 times as much DNA (DAPI fluorescence) as wild type histoblast nuclei.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference

esg35Ce-1/esg[+] is a suppressor of visible | dominant phenotype of gcmPyx

NOT Suppressor of
Statement
Reference

esg35Ce-1/esg[+] is a non-suppressor of bang sensitive phenotype of parabss1

Phenotype Manifest In
Suppressor of
Statement
Reference

esg35Ce-1/esg[+] is a suppressor of chaeta | increased number phenotype of gcmPyx

Additional Comments
Genetic Interactions
Statement
Reference

eas2/+ ; esg35Ce-1/+ double heterozygous females show no bang sensitivity. The bang sensitivity of bss1/+ flies is not significantly altered by esg35Ce-1/+.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer

Simpson.

P. Simpson.

Comments
Comments

Phenotypic data included in FBrf0051973.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (8)
References (16)