FB2026_02 , released June 18, 2026
Allele: Dmel\eve2
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General Information
Symbol
Dmel\eve2
Species
D. melanogaster
Name
FlyBase ID
FBal0003884
Feature type
allele
Associated gene
Dmel\eve
Associated Insertion(s)
Carried in Construct
Also Known As
eveIIR59, eveIIR
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Vincent et al., 1997)
Mutagen
ethyl methanesulfonate
(Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description

Amino acid replacement: T75I.

(Frasch et al., 1988)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:9,979,709..9,979,709 [+]
Nucleotide change:

C9979709T

Amino acid change:

T75I | eve-PA

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change

(Frasch et al., 1988)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Cephalic furrow formation occurs normally in homozygous embryos.

      (Vincent et al., 1997)

      Weak allele.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      eve2 is an enhancer of lethal | embryonic stage | maternal effect phenotype of Gug03928

      (Zhang et al., 2002)

      eve2 is an enhancer of lethal | embryonic stage | maternal effect phenotype of Guge46-2

      (Zhang et al., 2002)

      eve2 is an enhancer of lethal | embryonic stage | maternal effect phenotype of Gug01323a

      (Zhang et al., 2002)

      eve2 is an enhancer of lethal | embryonic stage | maternal effect phenotype of GugrO154a

      (Zhang et al., 2002)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      eve2
      eveIIR59
      (Vincent et al., 1997, Harbecke and Lengyel, 1995, Frasch et al., 1988)
      eveIIR
      (Li and Noll, 1993, Coulter and Wieschaus, 1988, Tearle and Nusslein-Volhard, 1987)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)