FlyBase Allele Report: Dmel\Gug[01323a]

General Information

Symbol

Dmel\Gug^01323a

Species

D. melanogaster

Name

FlyBase ID

FBal0090387

Feature type

allele

Associated gene

Dmel\Gug

Associated Insertion(s)

P{PZ}Gug^01323a

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Zhang et al., 2002, Nicholls and Gelbart, 1998)

Progenitor genotype

Associated Insertion(s)

P{PZ}Gug^01323a

Cytology

Description

The P{PZ} insertion is located within the second .

(Zhang et al., 2002)

Allele components

Component

Use(s)

Inserted element

P{PZ}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of dentatorubral-pallidoluysian atrophy

CEA with Gug^rO154a

(Zhang et al., 2002)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during embryonic stage | maternal effect

(Zhang et al., 2002)

some die during embryonic stage | maternal effect

(Zhang et al., 2002)

Phenotype Manifest In

Detailed Description

Statement

Reference

Embryos laid by heterozygous mothers survive normally.

(Zhang et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Gug^01323a has lethal | embryonic stage | maternal effect phenotype, enhanceable by eve³

(Zhang et al., 2002)

Gug^01323a has lethal | embryonic stage | maternal effect phenotype, enhanceable by eve¹

(Zhang et al., 2002)

Gug^01323a has lethal | embryonic stage | maternal effect phenotype, enhanceable by eve²

(Zhang et al., 2002)

Gug^01323a has lethal | embryonic stage | maternal effect phenotype, enhanceable by eve⁴

(Zhang et al., 2002)

Gug^01323a has lethal | embryonic stage | maternal effect phenotype, enhanceable by hkb⁶²

(Zhang et al., 2002)

Gug^01323a has lethal | embryonic stage | maternal effect phenotype, enhanceable by hkb^A321R1

(Zhang et al., 2002)

Gug^01323a has lethal | embryonic stage | maternal effect phenotype, enhanceable by hkb^XM9

(Zhang et al., 2002)

Phenotype Manifest In

Other

Statement

Reference

Gug^01323a, eve³ has abdominal 4 ventral denticle belt phenotype

(Zhang et al., 2002)

Gug^01323a, eve³ has abdominal 8 ventral denticle belt phenotype

(Zhang et al., 2002)

Gug^01323a, eve³ has abdominal 2 ventral denticle belt phenotype

(Zhang et al., 2002)

Gug^01323a, eve³ has abdominal 6 ventral denticle belt phenotype

(Zhang et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

When eve³/- males are mated with heterozygous Gug^01323a mothers practically no embryos survive. These embryos die at late embryonic stage, they lose some or all of the even numbered ventral denticle belts. When the opposite cross (eve³/+ mother, Gug^01323a/+ fathers) no reduction in survival is seen. When hkb^XM9/- males are mated with heterozygous Gug^01323a mothers only a quarter of the expected number of embryos survive. When the opposite cross (hkb^XM9/+ mother, Gug^01323a/+ fathers) no reduction in survival is seen.

(Zhang et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Gug⁰³⁹²⁸

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Complements: h⁰¹⁶²⁰. Complements: h⁰⁸²⁴⁷. Complements: cpo⁰⁸⁴³⁵. Complements: Prm¹⁰⁶³¹.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

Atro^01323a

Gug^01323a

(Zhang et al., 2002)

l(3)01323

(Zhang et al., 2002, Beaton, 1999.12.12)

l(3)01323⁰¹³²³

(Nicholls and Gelbart, 1998)

l(3)03928^01323a

(BDGP Project Members, 1994-1999)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

Open Close