FB2026_02 , released June 18, 2026
Allele: Dmel\hkb62
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General Information
Symbol
Dmel\hkb62
Species
D. melanogaster
Name
FlyBase ID
FBal0051515
Feature type
allele
Associated gene
Dmel\hkb
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Chu-LaGraff et al., 1995)
Mutagen
P-element activity
(Lundell et al., 1996, Chu-LaGraff et al., 1995)
Progenitor genotype
P{lacW}hkbs5953
(Lundell et al., 1996, Chu-LaGraff et al., 1995)
Cytology
Description

Imprecise excision of the progenitor insertion.

(Lundell et al., 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant embryos show a large reduction in the number of denticles, and those remaining are reduced in pigmentation. The mouthparts and posterior spiracles are reduced in pigmentation. Only approximately 20% of the expected number of ventral ganglion serotonin-expressing neurons are seen in the mutant embryos.

      (Lundell et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      hkb62 is an enhancer of lethal | embryonic stage | maternal effect phenotype of Gug01323a

      (Zhang et al., 2002)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Q. Chu-LaGraff.

      (Chu-LaGraff et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      hkb62
      (Lundell et al., 1996)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)