FB2026_02 , released June 18, 2026
Allele: Dmel\fs(1)h18
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General Information
Symbol
Dmel\fs(1)h18
Species
D. melanogaster
Name
FlyBase ID
FBal0004295
Feature type
allele
Associated gene
Dmel\fs(1)h
Associated Insertion(s)
Carried in Construct
Also Known As
fshE
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
PM hybrid dysgenesis
male recombination induced by dysgenesis
(Eeken et al., 1985)
MRh12 induced male recombination
(Digan et al., 1986)
Progenitor genotype
Cytology
Description

Duplication of sequences found from position 37 to 47 on the wild-type map (the origin of molecular coordinates is a SacI site just proximal to the proximal breakpoint of Df(1)C128, positive values to the left). The two duplicated sections are separated by a non-duplicated stretch of approximately 800bp.

(Digan et al., 1986)

8kb duplication in the fs(1)h gene.

(Eeken et al., 1985)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Males carrying fs(1)h18 die during larval stages.

      (Digan et al., 1986)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      Nipped-B[+]/Nipped-B407, fs(1)h18 has partially lethal | dominant phenotype

      (Luna-Peláez et al., 2019)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      fs(1)hrnc

      (Florence and Faller, 2008)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Relative strengths of the mutant alleles estimated as follows: Df(1)C128 = fs(1)h5 = fs(1)h4 > fs(1)h18 > fs(1)h3 > fs(1)h8 > fs(1)h17 > fs(1)h2 > fs(1)h6 > fs(1)h1.

      Identification: Failure to complement the temperature sensitive sterility of fs(1)h1 or fs(1)h2. Relative strengths of the mutant alleles estimated as follows: fs(1)h2 > fs(1)h6 > fs(1)h1 for the temperature sensitive alleles, Df(1)C128 = fs(1)h5 = fs(1)h4 > fs(1)h18 > fs(1)h3 > fs(1)h8 > fs(1)h17 for the non-conditional alleles.

      (Digan et al., 1986)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      28/62A
      (Eeken et al., 1985)
      fs(1)h18
      (Popodi et al., 2010-)
      fs(1)h18
      (Luna-Peláez et al., 2019, Florence and Faller, 2008)
      fshE
      (Haynes et al., 1989, Digan et al., 1986)
      l(1)28/62A
      Name Synonyms
      Secondary FlyBase IDs
        References (6)