FlyBase Allele Report: Dmel\Gs1[1]

General Information

Symbol

Dmel\Gs1¹

Species

D. melanogaster

Name

FlyBase ID

FBal0005224

Feature type

allele

Associated gene

Dmel\Gs1

Associated Insertion(s)

Carried in Construct

Also Known As

GSI^C7

Key Links

Allele class

amorphic allele - genetic evidence

loss of function allele

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Caggese et al., 1988)

loss of function allele

Mutagen

ethyl methanesulfonate

(Caggese et al., 1994, Caggese et al., 1988)

Progenitor genotype

Gs1^s

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile (with Gs1^MI09526)

(Miller et al., 2020)

lethal

(Caggese et al., 1988)

lethal (with Df(2L)ED5878)

(Kahsai and Cook, 2018)

lethal (with Df(2L)PMG)

(Miller et al., 2020)

lethal (with Gs1^G3347)

(Miller et al., 2020)

Phenotype Manifest In

embryonic somatic muscle cell (with Df(2L)PM1)

(Artero et al., 2003)

muscle attachment site (with Df(2L)PM1)

(Artero et al., 2003)

muscle cell of A1-7 dorsal oblique muscle 2 (with Df(2L)PM1)

(Artero et al., 2003)

Detailed Description

Statement

Reference

Gs1¹/Df(2L)PM1 embryos have defects in the somatic muscles; the dorsal muscles are sometimes split in two, the DO2 muscle is thinner than normal and the dorsal muscles have aberrant attachment to the apodemes.

(Artero et al., 2003)

Female sterile when heterozygous with Gs1^PM11-19 or Df(2L)PM1.

(Caggese et al., 1992)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Gs1¹ is a suppressor of decreased cell number | oogenesis phenotype of Acc^HMS01230, Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

Phenotype Manifest In

Suppressor of

Statement

Reference

Gs1¹ is a suppressor of female fusome phenotype of Acc^HMS01230, Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

Gs1¹ is a suppressor of female germline cyst phenotype of Acc^HMS01230, Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

Gs1¹ is a suppressor of female germline stem cell | decreased number phenotype of Acc^HMS01230, Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

6248

w¹; Gs1¹/CyO

Notes on Origin

Discoverer

Comments

Gs2 activity not modified.

(Caggese et al., 1988)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

(Caggese et al., 1994)

GSI^C7

(Caggese et al., 1992, Caggese et al., 1988)

Gs1¹

(Amartuvshin et al., 2025, Kahsai and Cook, 2018)

l(2)C7

(Larsson et al., 1996)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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