FB2026_02 , released June 18, 2026
Allele: Dmel\Adf101349
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General Information
Symbol
Dmel\Adf101349
Species
D. melanogaster
Name
FlyBase ID
FBal0007970
Feature type
allele
Associated gene
Dmel\Adf1
Associated Insertion(s)
P{PZ}Adf101349
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
Progenitor genotype
Associated Insertion(s)
P{PZ}Adf101349
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      abdominal dorsal multidendritic neuron ddaE & dendrite

      (Parrish et al., 2006)

      dorsal multidendritic neuron ddaE & dendrite

      (Parrish et al., 2006)
      Detailed Description
      Statement
      Reference

      Class I dendritic arbors of Adf101349 mutants are indistinguishable from wild-type neurons until 96 h after egg laying (AEL). By 144 h AEL, ddaE arbors of Adf101349 mutants showed a greater than twofold increase in branch number when compared with time-matched wild-type controls. In contrast, ddaD neurons show only very minor branching defects in these mutants.

      (Parrish et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Adf1[+]/Adf101349 is an enhancer of visible | dominant phenotype of Pc3

      (Orsi et al., 2014)

      Adf1[+]/Adf101349 is an enhancer of homeotic | dominant phenotype of Pc3

      (Orsi et al., 2014)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Adf1[+]/Adf101349 is an enhancer of mesothoracic leg phenotype of Pc3

      (Orsi et al., 2014)

      Adf1[+]/Adf101349 is an enhancer of metathoracic leg phenotype of Pc3

      (Orsi et al., 2014)

      Adf1[+]/Adf101349 is an enhancer of sex comb | ectopic phenotype of Pc3

      (Orsi et al., 2014)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Adf101349/+ enhances the ectopic sex comb phenotype seen in Pc3/+ males. The double heterozygotes have ectopic sex combs on the second leg (90% penetrance) and on the third leg (75% penetrance).

      (Orsi et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      Comments
      Comments

      Complements: l(2)0032900329. Complements: jing01094. Complements: l(2)0128901289. Complements: l(2)0305503055. Complements: l(2)04535b04535b. Complements: l(2)04535b04543. Complements: l(2)04535b05862. Complements: jing07111. Complements: jing07112. Complements: l(2)0128907769. Complements: l(2)1052110521. Complements: l(2)04535bk09819. Complements: geminink14019. Complements: l(2)04535bk14807.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Adf101349
      (Kahsai et al., 2016, Orsi et al., 2014, Parrish et al., 2006)
      l(2)01349
      (Spradling et al., 1999)
      l(2)0134901349
      (Meister and Braun, 1995.10, BDGP Project Members, 1994-1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)