FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Cul202074
Open Close
General Information
Symbol
Dmel\Cul202074
Species
D. melanogaster
Name
FlyBase ID
FBal0007993
Feature type
allele
Associated gene
Dmel\Cul2
Associated Insertion(s)
P{PZ}Cul202074
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
Progenitor genotype
Associated Insertion(s)
P{PZ}Cul202074
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      larval brain | restricted
      (Ayyub, 2011)
      eye disc posterior to the morphogenetic furrow
      (Ayyub, 2011)
      antennal disc | restricted
      (Ayyub, 2011)
      arista | precursor
      (Ayyub, 2011)
      adult stage
      ovary
      (Ayyub, 2011)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Cul2
      (Ayyub, 2011)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Cul-2EY09124/Cul-202074 larvae show a significant increase in bouton number (counted from muscles 6 and 7 of abdominal segment A2), compared to controls.

      (Ayyub, 2011)

      Heterozygotes with Df(2L)305 or Df(2L)TE38A-2 are lethal.

      (Kerridge, 1996.11.6)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Cul202074 is a suppressor of visible phenotype of Scer\GAL4GMR.PF, cindrRNAi.PC.PD.UAS

      (Ketosugbo et al., 2017)
      Other
      Statement
      Reference

      Cul202074, tsh8 has viable phenotype

      (Kerridge, 1996.11.6)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Cul202074 is a suppressor of eye phenotype of Scer\GAL4GMR.PF, cindrRNAi.PC.PD.UAS

      (Ketosugbo et al., 2017)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Heterozygotes with tsh8 are viable.

      (Kerridge, 1996.11.6)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Cul205230

      (BDGP Project Members, 1994-1999)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      Comments
      Comments

      Complements: l(2)03832a03832a. Complements: tsh04319. Complements: l(2)03832ak05429a. Complements: l(2)k08110k08110. Complements: l(2)k08110k11104.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (7)
      Reported As
      Symbol Synonym
      Cul-202074
      Cul202074
      cul-202074
      cul-2PlacZ
      (Ayyub, 2011)
      cul2PlacZ
      (Ayyub, 2011)
      l(2)02074
      (Khush, 2003.2.25, Misra, 2000.8.25, Spradling et al., 1999)
      l(2)0207402074
      (Kerridge, 1996.11.6, BDGP Project Members, 1994-1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (11)