FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tsh04319
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General Information
Symbol
Dmel\tsh04319
Species
D. melanogaster
Name
FlyBase ID
FBal0008056
Feature type
allele
Associated gene
Dmel\tsh
Associated Insertion(s)
P{PZ}tsh04319
Carried in Construct
Also Known As
l(2)04319
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Kerridge, 1996.11.6)
Progenitor genotype
Associated Insertion(s)
P{PZ}tsh04319
Cytology
Description

Insertion of P{PZ} into tsh untranslated leader sequences.

(Soanes and Bell, 1999)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      tsh8/tsh04319 and Df(2L)305/tsh04319 heterozygotes are lethal. Viable with Df(2L)TE38A-2.

      (Kerridge, 1996.11.6)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Complements

      tshR6

      (Soanes and Bell, 1999)
      Fails to complement

      tsh8

      (Soanes and Bell, 1999)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      Comments
      Comments

      Mobilization of the P{PZ} leads to generation of tsh alleles at relatively high frequency. All of the resulting tsh mutants remain mutant for tsh.

      (Soanes and Bell, 1999)

      Complements: Nipped-B02047. Complements: cul-202074. Complements: l(2)03832a03832a. Complements: l(2)k16406k16406. Complements: l(2)rAO135rAO135.

      (BDGP Project Members, 1994-1999)

      Strong tsh allele.

      (Kerridge, 1996.11.6)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      l(2)04319
      (Yan et al., 2002, Spradling et al., 1999)
      l(2)0431904319
      tsh04319
      (Rubio-Ferrera et al., 2023, Jordan et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (14)