FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sr03999
Open Close
General Information
Symbol
Dmel\sr03999
Species
D. melanogaster
Name
FlyBase ID
FBal0009498
Feature type
allele
Associated gene
Dmel\sr
Associated Insertion(s)
P{PZ}sr03999
Carried in Construct
Also Known As
l(3)03999, sr-lacZ, srP1618
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Beiman et al., 1996, Frommer et al., 1996, Lindsley and Zimm, 1992)
Progenitor genotype
Associated Insertion(s)
P{PZ}sr03999
Cytology
Description

P{PZ} insertion into an intron.

(Beiman et al., 1996)

P{PZ} insertion within the intron that separates the different 5' regions from the common 3' region of transcripts sra and srb.

(Frommer et al., 1996)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Semi-lethal.

      (Frommer et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      sr03999 has mesonotum phenotype, enhanceable by ap4/ap4

      (Ghazi et al., 2000)

      sr03999 has adult epidermis phenotype, enhanceable by ap4/ap4

      (Ghazi et al., 2000)
      Enhancer of
      Statement
      Reference

      sr03999/sr03999 is an enhancer of indirect flight muscle cell phenotype of ap4

      (Ghazi et al., 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      A significant proportion of ap4/ap4, sr03999/sr03999 flies show an enhanced IFM mutant phenotype and a dark midnotal stripe characteristic of strong sr mutants.

      (Ghazi et al., 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      (Lindsley and Zimm, 1992)
      Comments
      Comments

      Complements: l(3)0064300643. Complements: l(3)0569705697. Complements: Ssdpneo48. Fails to complement: l(3)00643s2541.

      (BDGP Project Members, 1994-1999)

      Δ2-3 mobilisation of the P{PZ} insertion causing a precise excision reverts the mutant phenotype to wild type.

      (Frommer et al., 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      l(3)03999
      (Usui et al., 2004, Dorfman et al., 2002, Spradling et al., 1999)
      l(3)0399903999
      (Lindsley and Zimm, 1992)
      sr03999
      srP1618
      (Inbal et al., 2004, Beiman et al., 1996)
      Name Synonyms
      Secondary FlyBase IDs
        References (12)