FlyBase Allele Report: Dmel\kra[j9B6]

General Information

Symbol

Dmel\kra^j9B6

Species

D. melanogaster

Name

FlyBase ID

FBal0011006

Feature type

allele

Associated gene

Dmel\kra

Associated Insertion(s)

P{lacW}kra^j9B6

Carried in Construct

Also Known As

l(3)j9B6

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

Progenitor genotype

Associated Insertion(s)

P{lacW}kra^j9B6

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:5,601,080..5,601,080 [+]

(Lee et al., 2007, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates fragile X-associated tremor/ataxia syndrome

modeled by Zzzz\CGG^103.UAS.EGFP

(Singh et al., 2021)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

kra[+]/kra^j9B6 is an enhancer of visible | adult stage phenotype of Scer\GAL4^GMR.PF, Zzzz\CGG^90.UAS.EGFP

(Singh et al., 2021)

Other

Statement

Reference

Scer\GAL4^GMR.PF, Zzzz\CGG^90.UAS.EGFP, kra[+]/kra^j9B6 has increased cell death | adult stage phenotype

(Singh et al., 2021)

Phenotype Manifest In

Enhancer of

Statement

Reference

kra[+]/kra^j9B6 is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, Zzzz\CGG^90.UAS.EGFP

(Singh et al., 2021)

kra[+]/kra^j9B6 is an enhancer of ommatidium phenotype of Scer\GAL4^GMR.PF, Zzzz\CGG^90.UAS.EGFP

(Singh et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

The rough eye phenotype induced by the expression of Zzzz\CGG^90.UAS.EGFP under the control of Scer\GAL4^GMR.PF is enhanced by kra^j9B6, even leading to some necrosis.

(Singh et al., 2021)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

10216

y¹ w¹¹¹⁸; P{lacW}kra^j9B6/TM3, Sb¹

Kyoto

111026

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{neoFRT}82B P{lacW}kra^j9B6/TM6B, P{Car20y}TPN1, Tb¹

Notes on Origin

Discoverer

Comments

Insertion of a P{lacW} element at -1636 of the exba open reading frame.

(Lee et al., 2007)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

Kra^j9B6

(Singh et al., 2021)

exba^j9B6

kra^j9B6

l(3)j9B6

(Spradling et al., 1999)

l(3)j9B6^j9B6

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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