FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Set81
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General Information
Symbol
Dmel\Set81
Species
D. melanogaster
Name
FlyBase ID
FBal0011054
Feature type
allele
Associated gene
Dmel\Set8
Associated Insertion(s)
P{hsneo}Set81
Carried in Construct
Also Known As
l(3)neo41, pr-set71
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Fang et al., 2002)
Mutagen
P-element activity
(Cooley et al., 1988)
Progenitor genotype
Associated Insertion(s)
P{hsneo}Set81
Cytology
Description

Insertion of P{hsneo} in the 5'UTR of pr-set7, 123 bp downstream of the predicted transcription start site.

(Fang et al., 2002)

Insertion of P{hsneo} into exon 1, in the predicted 5'UTR of pr-set7.

(Nishioka et al., 2002)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Melanisations are rare in pr-set71/Df(3R)red3l third instar larvae and are only found in the gut and cuticle.

      (Minakhina and Steward, 2006)

      pr-set71/pr-set720 escapers generally die soon after eclosion and the eye is reduced in size and irregular in these animals.

      (Karachentsev et al., 2005)

      Rare adult escapers of lethality, when heterozygous with Df(3R)red3l, show rough eyes, notched wings and disorganised bristles. Lethality occurring befroe adulthood is pupal and prepupal.

      (Fang et al., 2002)

      Homozygous mutants die as late second instar larvae.

      (Nishioka et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Cooley et al.

      (Cooley et al., 1988)
      Comments
      Comments

      Homozygous larvae show complete failure of methylation at K20 of His4.

      (Nishioka et al., 2002)

      Mutant larvae show significantly reduced methylation at K20 of His4.

      (Fang et al., 2002)

      Complements: putj5A5.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      PR-Set71
      (Song et al., 2018)
      Set81
      (Crain et al., 2022)
      l(3)neo41
      (Karachentsev et al., 2005, Fang et al., 2002, Spradling et al., 1999)
      l(3)neo411
      (BDGP Project Members, 1994-1999, Cooley et al., 1988)
      pr-Set7P{hsneo}1
      (Minakhina and Steward, 2006)
      pr-set71
      (Debruhl et al., 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (10)