FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mam21
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General Information
Symbol
Dmel\mam21
Species
D. melanogaster
Name
FlyBase ID
FBal0012029
Feature type
allele
Associated gene
Dmel\mam
Associated Insertion(s)
Carried in Construct
Also Known As
mamZ3
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The number of cells in the nau-expressing muscle precursor clusters is increased compared to wild-type in homozygous embryos.

      (Rusconi and Corbin, 1998)

      Homozygous embryos have an increased number of cardiac precursor cells.

      (Jagla et al., 1997)

      Embryonic CNS exhibits severe disturbances and larval exhibit moderate cuticle loss.

      (Schmid et al., 1996)

      Adult escapers of mamKE372/mam21 have strong enhancement of the wing phenotype: notches on wing margin, thickening of vein 2.

      (Brand and Campos-Ortega, 1990)

      mam21 expression was modified by the presence of ASC loss-of-function mutations.

      (Brand and Campos-Ortega, 1988)

      Extreme allele. Heterozygotes show delta-like widenings of wing veins L2, L3 and L4 at the margins of the wings.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      mam21 is an enhancer of visible phenotype of Scer\GAL4455.2, l(1)scUAS.cHa

      (Rottgen et al., 1998)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      mam21 is an enhancer of scutellar bristle phenotype of Scer\GAL4455.2, l(1)scUAS.cHa

      (Rottgen et al., 1998)
      NOT Suppressor of
      Statement
      Reference

      mam21 is a non-suppressor of phenotype of Src42ASu(Raf)1-1

      (Zhang et al., 1999)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Does not suppress the ability of Src42ASu(phl)1-1 to suppress the lethality of phl1/Y flies.

      (Zhang et al., 1999)

      Mutation enhances the ectopic scutellar bristle phenotype seen from Scer\GAL4455.2-mediated expression of l(1)scScer\UAS.cHa.

      (Rottgen et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Wetter.

      Comments
      Comments

      Strong mam allele.

      (Brand and Campos-Ortega, 1990)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      References (9)