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General Information
Symbol
Dmel\Src42ASu(Raf)1-1
Species
D. melanogaster
Name
FlyBase ID
FBal0039065
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Src42ASu(Raf)1
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous clones in the eye do not produce extra photoreceptor cells. Src42ASu(phl)1-1/Df(2R)nap9 animals show defects in head involution, tail morphology and tracheal necrosis.

Heterozygotes are viable with no obvious phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference

Src42ASu(Raf)1-1 is a suppressor of visible | recessive phenotype of Dsor1XS520

Src42ASu(Raf)1-1 is a suppressor of visible | recessive phenotype of Sosx122

Src42ASu(Raf)1-1 is a suppressor of visible | recessive phenotype of Raf1

Src42ASu(Raf)1-1 is a suppressor of visible | recessive phenotype of SosAM14

Src42ASu(Raf)1-1 is a suppressor of lethal | recessive phenotype of Raf1

Src42ASu(Raf)1-1 is a suppressor of lethal | pupal stage | heat sensitive phenotype of Raf12

Src42ASu(Raf)1-1 is a suppressor of lethal phenotype of Dsor1LH110

NOT Suppressor of
Statement
Reference

cnksag13L/Src42ASu(Raf)1-1 is a non-suppressor of lethal phenotype of Raf1

Src42ASu(Raf)1-1/cnksag32-3 is a non-suppressor of lethal phenotype of Raf1

Other
Phenotype Manifest In
Suppressed by
Statement
Reference

Src42ASu(Raf)1-1 has phenotype, suppressible by Egfr[+]/Egfrunspecified

Src42ASu(Raf)1-1 has phenotype, suppressible by Egfr[+]/Egfrf24

Src42ASu(Raf)1-1 has phenotype, suppressible by S[+]/SIIN

Src42ASu(Raf)1-1 has phenotype, suppressible by rho7M43/rho[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by 14-3-3ζ07103/14-3-3zeta[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by bowl85/bowl[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by bowl2-17-29-5/bowl[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by Su(tor)2-164-14[+]/Su(tor)2-164-142-164-14

Src42ASu(Raf)1-1 has phenotype, suppressible by Su(tor)278-22[+]/Su(tor)278-22278-22

Src42ASu(Raf)1-1 has phenotype, suppressible by Su(tor)2-113-312-113-31/Su(tor)2-113-31[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by Su(tor)2-68-20[+]/Su(tor)2-68-202-68-20

Src42ASu(Raf)1-1 has phenotype, suppressible by Su(tor)2-321[+]/Su(tor)2-3211

Src42ASu(Raf)1-1 has phenotype, suppressible by rl[+]/rl10

Src42ASu(Raf)1-1 has phenotype, suppressible by Su(H)8/Su(H)[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by Serrev6-1/Ser[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by Egfr[+]/Egfr40-6

Src42ASu(Raf)1-1 has phenotype, suppressible by Egfr[+]/Egfr30-1

Src42ASu(Raf)1-1 has phenotype, suppressible by Egfr[+]/Egfr9-2

Src42ASu(Raf)1-1 has phenotype, suppressible by Egfr[+]/Egfr24-1

Src42ASu(Raf)1-1 has phenotype, suppressible by Egfr[+]/Egfr26-3

Src42ASu(Raf)1-1 has phenotype, suppressible by Egfr[+]/Egfr4

Src42ASu(Raf)1-1 has phenotype, suppressible by Egfr[+]/Egfr5

Src42ASu(Raf)1-1 has phenotype, suppressible by Egfr[+]/Egfr6

Src42ASu(Raf)1-1 has phenotype, suppressible by drk[+]/drkΔP24

Src42ASu(Raf)1-1 has phenotype, suppressible by Egfr[+]/Egfr9

Src42ASu(Raf)1-1 has phenotype, suppressible by Egfr[+]/Egfr15

Src42ASu(Raf)1-1 has phenotype, suppressible by Egfr[+]/Egfr27

Src42ASu(Raf)1-1 has phenotype, suppressible by rl41-1/rl[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by rl[+]/rlA3-2

Src42ASu(Raf)1-1 has phenotype, suppressible by cnk16-2/sag[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by cnk8/sag[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by sag[+]/cnk16

Src42ASu(Raf)1-1 has phenotype, suppressible by cnk18/sag[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by cnk33/sag[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by Sosx122/Sos[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by cnksag13L/sag[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by Su(SuRaf1)IVA7-2/Su(SuRaf1)IV[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by Su(SuRaf1)IV4/Su(SuRaf1)IV[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by Su(SuRaf1)19-2[+]/Su(SuRaf1)19-219-2

Src42ASu(Raf)1-1 has phenotype, suppressible by Su(SuRaf1)A2-1[+]/Su(SuRaf1)A2-1A2-1

Src42ASu(Raf)1-1 has phenotype, suppressible by Su(SuRaf1)1[+]/Su(SuRaf1)11

Src42ASu(Raf)1-1 has phenotype, suppressible by Su(SuRaf1)2[+]/Su(SuRaf1)22

Src42ASu(Raf)1-1 has phenotype, suppressible by Su(SuRaf1)10[+]/Su(SuRaf1)1010

Src42ASu(Raf)1-1 has phenotype, suppressible by Su(SuRaf1)1111/Su(SuRaf1)11[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by Su(SuRaf1)12[+]/Su(SuRaf1)1212

Src42ASu(Raf)1-1 has phenotype, suppressible by Sos[+]/Sos34Ea-6

Src42ASu(Raf)1-1 has phenotype, suppressible by Ras85De2F/Ras85D[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by Df(2R)M41A10

Src42ASu(Raf)1-1 has phenotype, suppressible by Df(2L)ast2

Src42ASu(Raf)1-1 has phenotype, suppressible by Ras85De1B/Ras85D[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by Ras85D05703/Ras85D[+]

Src42ASu(Raf)1-1 has phenotype, suppressible by spi[+]/spiSC1

NOT suppressed by
Statement
Reference

Src42ASu(Raf)1-1 has phenotype, non-suppressible by Ras85DΔC40B

Src42ASu(Raf)1-1 has phenotype, non-suppressible by spi1

Src42ASu(Raf)1-1 has phenotype, non-suppressible by vnddd-4

Src42ASu(Raf)1-1 has phenotype, non-suppressible by bowl2-60-20

Src42ASu(Raf)1-1 has phenotype, non-suppressible by Su(tor)2-187-22-187-2

Src42ASu(Raf)1-1 has phenotype, non-suppressible by Su(tor)2-280-282-280-28

Src42ASu(Raf)1-1 has phenotype, non-suppressible by Su(tor)2-341-392-341-39

Src42ASu(Raf)1-1 has phenotype, non-suppressible by Su(tor)2-28-232-28-23

Src42ASu(Raf)1-1 has phenotype, non-suppressible by bib7

Src42ASu(Raf)1-1 has phenotype, non-suppressible by neur11

Src42ASu(Raf)1-1 has phenotype, non-suppressible by mam21

Src42ASu(Raf)1-1 has phenotype, non-suppressible by tkv7

Src42ASu(Raf)1-1 has phenotype, non-suppressible by Mad12

Src42ASu(Raf)1-1 has phenotype, non-suppressible by rl13R

Src42ASu(Raf)1-1 has phenotype, non-suppressible by put135

Src42ASu(Raf)1-1 has phenotype, non-suppressible by Df(3R)Espl4

Src42ASu(Raf)1-1 has phenotype, non-suppressible by Df(3R)Dl-M2

Suppressor of
Statement
Reference

Src42ASu(Raf)1-1 is a suppressor of eye phenotype of Dsor1XS520

Src42ASu(Raf)1-1 is a suppressor of eye phenotype of Sosx122

Src42ASu(Raf)1-1 is a suppressor of eye phenotype of Raf1

Src42ASu(Raf)1-1 is a suppressor of ommatidium phenotype of Raf1

Src42ASu(Raf)1-1 is a suppressor of eye phenotype of SosAM14

Src42ASu(Raf)1-1 is a suppressor | partially of ommatidium phenotype of Raf1

Additional Comments
Genetic Interactions
Statement
Reference

Suppresses the lethality of phl1. Lethality at the pupal stage is seen in Src42ASu(phl)1-1 Ras85DV12.sev or Src42ASu(phl)1-1 phl::tor13D.hs.sev double heterozygotes. The rough eye phenotype of hemizygous phl1 pharate adult males is also suppressed by Src42ASu(phl)1-1. Dominantly suppresses the rough eye phenotype of Dsor1XS520 and Sosx122/SosAM14.

Suppresses the phl1 phenotype; phl1/Y flies die, whereas phl1/Y ; Src42ASu(phl)1-1/+ flies are viable and fertile. phl1/Y pharate adults have rough eyes and the R7 cell is missing in 88% of ommatidia. Rescued phl1/Y ; Src42ASu(phl)1-1/+ flies have rough eyes and the R7 cell is missing in 36% of ommatidia. The ability of Src42ASu(phl)1-1 to suppress the lethality of phl1/Y flies is dominantly suppressed by Egfrunspecified, Egfrf24, rl10, Df(2R)M41A10, drkΔP24, Sosx122, Sos34Ea-6, Ras85De2F, Ras85De1B, Ras85D05703, spiSC1, Df(2L)ast2, SIIN, rho7M43, 14-3-3ζ07103, bowl85, bowl2-17-29-5, Su(tor)2-164-142-164-14, Su(tor)278-22278-22, Su(tor)2-113-312-113-31, Su(tor)2-68-202-68-20, Su(tor)2-3211, Su(H)8, Df(3R)Dl-M2, Serrev6-1, Egfr40-6, Egfr30-1, Egfr9-2, Egfr24-1, Egfr26-3, Egfr4, Egfr5, Egfr6, Egfr9, Egfr15, Egfr27, rl41-1, rlA3-2, rl21-1, rlZ3, rlZ7, rl19, sag32-3, sagA4-2, sag16-2, sag8, sag16, sag18, sag33, sag13L, Su(SuRaf1)IVA7-2, Su(SuRaf1)IV4, Su(SuRaf1)19-219-2, Su(SuRaf1)A2-1A2-1, Su(SuRaf1)11, Su(SuRaf1)22, Su(SuRaf1)1010, Su(SuRaf1)1111 or Su(SuRaf1)1212. The ability of Src42ASu(phl)1-1 to suppress the lethality of phl1/Y flies is not suppressed by Ras85DΔC40B, spi1, vnddd-4, bowl2-60-20, Su(tor)2-187-22-187-2, Su(tor)2-280-282-280-28, Su(tor)2-341-392-341-39, Su(tor)2-28-232-28-23, bib7, Df(3R)Espl4, neur11, mam21, tkv7, Mad12, rl13R or put135.

One copy is able to rescue the lethality of phl1, phl12 and Dsor1LH110 homozygotes, partially rescue the eye defect of phl1 male hemizygotes and allow phl1 homozygous females to produce few eggs with variable phenotype, fused or normal dorsal appendages.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (6)
Reported As
Symbol Synonym
Src42ASu(Raf)1-1
Src42ASu(phl)1-1
Su(phl)11
Name Synonyms
Secondary FlyBase IDs
    References (6)