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General Information
Symbol
Dmel\Dsor1LH110
Species
D. melanogaster
Name
FlyBase ID
FBal0039032
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
dSorLH110
Mutagen
    Nature of the Allele
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 1 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Mutant embryos show complete loss of the intermediate neuroblast column of the neuroectoderm.

    Dsor1LH110/+ flies show a wild-type number of rhabdomeres in their eyes.

    The mesoderm is able to make contact with and flatten against the ectoderm in a symmetric fashion in homozygous embryos derived from homozygous female germline clones.

    Embryos exhibit a dorsal open phenotype.

    Embryos derived from homozygous germ line clones fall into two phenotypic classes depending on paternal contribution. One class is completely rescued embryos and the second class of embryos differentiate cuticle but exhibit deletion of structures posterior to abdominal segment 7 and deletion of the acron.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Suppressed by
    Statement
    Reference

    Dsor1LH110 has lethal phenotype, suppressible by Su(phl)61

    Dsor1LH110 has lethal phenotype, suppressible by Su(phl)71

    Dsor1LH110 has lethal phenotype, suppressible by Su(phl)91

    Dsor1LH110 has lethal phenotype, suppressible by Src42ASu(Raf)1-1

    Dsor1LH110 has lethal phenotype, suppressible by Su(phl)43B1

    Dsor1LH110 has lethal phenotype, suppressible by Su(phl)41

    Enhancer of
    Statement
    Reference
    NOT Enhancer of
    Statement
    Reference
    Suppressor of
    Statement
    Reference
    NOT Suppressor of
    Phenotype Manifest In
    NOT suppressed by
    Statement
    Reference
    Enhancer of
    NOT Enhancer of
    Suppressor of
    Statement
    Reference
    NOT Suppressor of
    Other
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Dsor1LH110 sl1 double mutant border cell clusters (induced as clones) initiate migration, but are delayed later in posterior migration and do not show dorsal migration.

    Expression of S6kIIScer\UAS.T:Hsap\MYC, under the control of Scer\GAL4GMR.PF, causes a more severe roughened-eye phenotype and a greater loss of rhabdomeres when expressed in a Dsor1LH110/+ background than when expressed in a wild-type background.

    When Dsor1LH110 is added to slikScer\UAS.cHa, Scer\GAL4ptc-559.1 animals the overgrowth phenotype is partially suppressed.

    The rough eye phenotype, irregular ommatidial array and increased photoreceptor cell number caused by expression of Gef26EP388 under the control of Scer\GAL4GMR.PF are strongly suppressed by Dsor1LH110/+.

    The Dsor1LH110 dorsal open phenotype cannot be rescued by heat induced expression of JraAsp.hs.sev.

    Su(phl)6, Su(phl)43B, Su(phl)9, Src42A, Su(phl)7 and Su(phl)4 and Dsor1Su34B are able to rescue the lethality at the restrictive temperature.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Rescued by
    Comments

    Lethality can be rescued by the presence of Dsor1+t9.

    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (8)
    Reported As
    Name Synonyms
    Secondary FlyBase IDs
      References (19)