FlyBase Allele Report: Dmel\rl[41-1]

General Information

Symbol

Dmel\rl^41-1

Species

D. melanogaster

Name

FlyBase ID

FBal0095229

Feature type

allele

Associated gene

Dmel\rl

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Zhang et al., 1999)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Zhang et al., 1999)

Phenotype Manifest In

eye

(Zhang et al., 1999)

wing

(Zhang et al., 1999)

Detailed Description

Statement

Reference

rl¹/rl^41-1 flies have bent wings and rough eyes.

(Zhang et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

cnk^sag13L, rl^41-1 has visible | dominant phenotype

(Zhang et al., 1999)

Phenotype Manifest In

Suppressor of

Statement

Reference

rl^41-1/rl[+] is a suppressor of phenotype of Dsor1^Su34B

(Zhang et al., 1999)

rl^41-1/rl[+] is a suppressor of phenotype of Src42A^Su(Raf)1-1

(Zhang et al., 1999)

rl^41-1/rl[+] is a suppressor of phenotype of Su(Raf)43B^43B

(Zhang et al., 1999)

Other

Statement

Reference

cnk^sag13L, rl^41-1 has ommatidium phenotype

(Zhang et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

Dominantly suppresses the ability of Src42A^Su(phl)1-1, Su(Raf)43B^43B or Dsor1^Su34B to suppress the lethality of phl¹/Y flies. rl^41-1 sag^13L double heterozygotes have disorganised ommatidia, although the eyes of either single heterozygote are normal.

(Zhang et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

rl^unspecified

(Zhang et al., 1999)

Comments

Fails to complement strong loss of function rl alleles for viability.

(Zhang et al., 1999)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a mutation that dominantly suppresses the ability of Src42A^Su(phl)1-1 to suppress the lethality of phl¹/Y flies.

(Zhang et al., 1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

rl^41-1

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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