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General Information
Symbol
Dmel\Pc5
Species
D. melanogaster
Name
FlyBase ID
FBal0013555
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
PcT3
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous Pc5 adults have a strong Pc adult phenotype, with transformations of 2nd leg to 1st leg, wing to haltere, ventral wing margin to dorsal wing margin, and posterior wing to anterior wing. Pc22/Pc5 transheterozygotes are viable, with a weak incompletely penetrant Pc adult phenotype.

homozygous viable? partial transformations of second and third legs into first legs when homozygous.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement
Reference

Pc5 has phenotype, enhanceable by Hsc70-454.1

Other
Additional Comments
Genetic Interactions
Statement
Reference

ph-p602 ph-d401; Pc5/+ flies show a weak wing to haltere transformation. ph-p604 ph-d401; Pc5/+ flies show a weak wing to haltere transformation. Df(1)ph-601; Pc5/+ flies show a weak wing to haltere transformation. ph-p600 ph-d401; Pc5/+ flies show a weak wing to haltere transformation. ph-p603 ph-d401; Pc5/+ flies show a weak wing to haltere transformation.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Tiong.

Comments
Comments

Clonal analysis suggests that there is an early requirement for Pc activity in the determination of the 2nd leg, while it is required until differentiation in the wing disc.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (5)