FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\l(1)16Fc1
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General Information
Symbol
Dmel\l(1)16Fc1
Species
D. melanogaster
Name
FlyBase ID
FBal0013927
Feature type
allele
Associated gene
l(1)16Fc
Associated Insertion(s)
Carried in Construct
Also Known As
387
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(de la Pompa, 1994, Ferrus et al., 1990)
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Ferrus et al., 1990)
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mild shaking activity in heterozygotes. CGF action potentials are abnormal.

      (Ferrus et al., 1990)

      embryonic lethal Major lethal phase in the first larval instar. Somatic mosaics in the adult hypoderm show normal differentiation. Gynandromorphs show vibrating appendages in the mutant territory; also uncoordinated movement on the mutant side. Germ-line mosaics show a maternal-effect since the eggs produced by mutant ovarioles never develop beyond the gastrula stage, irrespective of the zygotic genotype.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      l(1)16Fc1, wupA8384 has partially lethal phenotype

      (de la Pompa, 1994)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Heterozygotes with wupA8384 are poorly viable.

      (de la Pompa, 1994)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Mutation in the maternal effect III (MEIII) region of the Sh complex.

      (Ferrus et al., 1990)

      Mutation within the maternal effect III (MEIII) region of the Sh complex.

      (de la Pompa, 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      387
      (Ferrus, 1999.3.4, de la Pompa, 1994, Ferrus et al., 1990)
      l(1)16Fc1
      l(1)387
      Name Synonyms
      Secondary FlyBase IDs
        References (3)