FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ScrP
Open Close
General Information
Symbol
Dmel\ScrP
Species
D. melanogaster
Name
FlyBase ID
FBal0015306
Feature type
allele
Associated gene
Dmel\Scr
Associated Insertion(s)
Carried in Construct
Also Known As
ScrScxP
Key Links
Allele class

gain of function allele

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

gain of function allele

(Boube et al., 1997, Pattatucci and Kaufman, 1991, Pattatucci et al., 1991)

hypomorphic allele - genetic evidence

(Pattatucci et al., 1991)
Mutagen
X ray
(Pattatucci et al., 1991)
Progenitor genotype
Caused by aberration
T(3;4)ScrP
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygous males have an average of 3.9 ectopic sex comb teeth per second leg. Heterozygous males have an average of 1.4 ectopic sex comb teeth per third leg. ScrP/Scr4; Dp(3;Y)77ab males have an average of 0.3 ectopic sex comb teeth per second leg and an average of 0.03 ectopic sex comb teeth per third leg.

      (Southworth and Kennison, 2002)

      ScrP homozygous mutant animals occasionally exhibit an ectopic distal sex comb on the T1 leg.

      (Boube et al., 2000)

      Dominant allele.

      (Lindsley and Zimm, 1992)

      Extra sex combs present on all six legs of males.

      (Pattatucci and Kaufman, 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      ScrP, skdpap-53 has prothoracic leg | distal phenotype, enhanceable by MED17s2956

      (Boube et al., 2000)

      ScrP, skdpap-53 has sex comb | ectopic phenotype, enhanceable by MED17s2956

      (Boube et al., 2000)

      ScrP has prothoracic leg | distal phenotype, enhanceable by skdpap-53

      (Boube et al., 2000)

      ScrP has sex comb | ectopic phenotype, enhanceable by skdpap-53

      (Boube et al., 2000)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The addition of skdpap-53/+ to ScrP animals leads to an enhancement of the ectopic distal sex comb phenotype seen in the T1 legs of these flies. MED17s2956, ScrP flies occasionally exhibit an ectopic distal sex comb on the T1 leg.

      (Boube et al., 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Pultz.

      (Lindsley and Zimm, 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      References (8)