FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SdhA5
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General Information
Symbol
Dmel\SdhA5
Species
D. melanogaster
Name
FlyBase ID
FBal0015383
Feature type
allele
Associated gene
Dmel\SdhA
Associated Insertion(s)
Carried in Construct
Also Known As
Sdh5
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Mast et al., 2008)
Mutagen
ethyl methanesulfonate
(Lindsley and Zimm, 1992, Lawrence, 1981)
Progenitor genotype
Cytology
Description

Amino acid replacement: G533D.

(Mast et al., 2008)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:19,392,903..19,392,903 [-]
Nucleotide change:

G19392903A

Amino acid change:

G533D | SdhA-PA; G533D | SdhA-PB; G533D | SdhA-PC

Reported amino acid change:

G533D

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Mast et al., 2008)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  Parkinson's disease 2
      modeled by park25
      (O'Hanlon et al., 2022)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Lawrence.

      (Lindsley and Zimm, 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Sdh5
      (Mast et al., 2008)
      SdhA5
      (O'Hanlon et al., 2022, Mast et al., 2008)
      sdh5
      (Lawrence, 1981)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)