Embryos produced by snk1/snk2 mothers are completely dorsallzed, lacking both ventral denticles and Filzkorper.
The mean ln (natural logarithm) circulating hemocyte concentration (CHC) value of snk2/snk1 larvae is statistically indistinguishable from that of control siblings. The ability of snk2/snk1 larvae to encapsulate L.boulardi eggs is not significantly different from the encapsulation activity of control larvae.
Embryos from snk1/snk2 mothers lack all ventral structures.
Bacterially challenged mutants exhibit a wild type Drs response. Pattern of response of CecA1 and CecA2 parallels that of Drs. Dpt and Dro remain fully inducible and pattern of expression of AttA and Def in intermediate.
Embryos produced by homozygous mothers show extreme dorsalized phenotype; only dorsally derived cuticle remains, resulting in a hollow tube of dorsal ectoderm. No paternal rescue, even by two doses of snk+; dorsalizes the expression of ftz such that entire ftz stripes in the blastoderm exhibit the wide dorsal conformation and do not narrow ventrally as is normal.
Perivitelline fluid from Tl and dl donors was capable of restoring polarized gastrulation movements and cuticular elements.
Dorsalized embryos: all cuticle cells along the dorsoventral axis behave like dorsal cells of the wild type embryo. zen expression pattern refines at stage 5, dpp pattern does not refine at all, twi and sna are expressed during late stages of embryogenesis.
Embryos derived from homozygous females are dorsalised.