Open Close
General Information
Symbol
Dmel\speck2
Species
D. melanogaster
Name
FlyBase ID
FBal0015981
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference

    7566bp 412 element is inserted in the 5'UTR in exon 1 of isoform RB of speck. The size, structure and location of the 412 insertion in speck2 is identical to that found in speck1 (the insertion in both mutants is represented by 412{}881 in the annotated reference genome). Although the speck2 mutant has a stronger phenotype than speck1, no additional change has been identified in two speck2 chromosomes compared to speck1.

    412 insertion in 5' UTR of AANAT1 (aka 'Dat').

    Insertion components
    412{}881
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    speck2/Df(2R)BSC356 adults exhibit ectopic pigmentation in the wing hinge and a slightly darker body color.

    speck2/speckMB02738 adults exhibit ectopic pigmentation in the wing hinge.

    speck2 pupal cases exhibit excess pigmentation at the anal pad.

    Body colour: dark; darker than sp1.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Suppressed by
    Statement
    Reference
    NOT Enhancer of
    NOT Suppressor of
    Phenotype Manifest In
    Suppressed by
    Statement
    Reference
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (123)
    Notes on Origin
    Discoverer

    Bridges, June 1925.

    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (8)