FlyBase Allele Report: Dmel\speck[MB02738]

General Information

Symbol

Dmel\speck^MB02738

Species

D. melanogaster

Name

FlyBase ID

FBal0192364

Feature type

allele

Associated gene

Dmel\speck

Associated Insertion(s)

Mi{ET1}speck^MB02738

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

Mi{ET1}speck^MB02738

Cytology

Description

Mi{ET1} insertion in the 5'UTR in exon 1 of isoform RB of speck.

(Spana et al., 2020)

Allele components

Component

Use(s)

Inserted element

Mi{ET1}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:24,154,726..24,154,726 [+]

(Spana et al., 2020, Bellen, 2007.4.5)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal body color | adult stage | recessive

(Spana et al., 2020)

visible | adult stage (with speck²)

(Spana et al., 2020)

visible | adult stage | recessive

(Spana et al., 2020)

Phenotype Manifest In

anal pad | P-stage

(Spana et al., 2020)

leg joint

(Spana et al., 2020)

scutellum

(Spana et al., 2020)

wing hinge

(Spana et al., 2020)

wing hinge (with speck²)

(Spana et al., 2020)

Detailed Description

Statement

Reference

speck^MB02738/speck^MB02738 adults exhibit darker body color, darker pigment to the thorax, and ectopic pigmentation in the wing hinge, the leg joints, at the region between the scutellum and the mesothoracic preepisternum.

speck²/speck^MB02738 adults exhibit ectopic pigmentation in the wing hinge.

speck^MB02738 pupal cases exhibit excess pigmentation at the anal pad.

(Spana et al., 2020)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

speck²/speck^MB02738 has visible | adult stage phenotype, suppressible by Bmor\AANAT^UAS.cOa/Scer\GAL4^Tub.PU

(Spana et al., 2020)

NOT Enhancer of

Statement

Reference

speck²/speck^MB02738 is a non-enhancer of abnormal body color | adult stage phenotype of Bmor\AANAT^UAS.cOa, Scer\GAL4^Tub.PU

(Spana et al., 2020)

NOT Suppressor of

Statement

Reference

speck²/speck^MB02738 is a non-suppressor of abnormal body color | adult stage phenotype of Bmor\AANAT^UAS.cOa, Scer\GAL4^Tub.PU

(Spana et al., 2020)

Phenotype Manifest In

Suppressed by

Statement

Reference

speck²/speck^MB02738 has wing hinge phenotype, suppressible by Bmor\AANAT^UAS.cOa/Scer\GAL4^Tub.PU

(Spana et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

speck²

(Spana et al., 2020)

speck¹

(Spana et al., 2020)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

23484

w¹¹¹⁸; Mi{ET1}speck^MB02738

Notes on Origin

Discoverer

Comments

Precise excision of the Mi{ET1} insertion reverts the speck mutant phenotype.

(Spana et al., 2020)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

AANAT1^MB02738

(Spana et al., 2020)

Dat^MB02738

(Bellen, 2007.4.5)

speck^MB02738

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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