FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\stg1
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General Information
Symbol
Dmel\stg1
Species
D. melanogaster
Name
FlyBase ID
FBal0016173
Feature type
allele
Associated gene
Dmel\stg
Associated Insertion(s)
Carried in Construct
Also Known As
stg4B51, stg4B
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Hartenstein and Posakony, 1990)
Mutagen
ethyl methanesulfonate
(Tearle et al., 1994, Lindsley and Zimm, 1992, Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygotes with DrMio and Dr1 are semi-lethal, 10-30% adults survive to eclosion, surviving adults exhibit reduced eye, deranged bristle pattern on the thorax, abdomen, legs and wing margins and locomotor defects so the flies could hardly move.

      (Tearle et al., 1994)

      Temperature-sensitive.

      (Lindsley and Zimm, 1992)

      Does not interact with RpII140wimp maternal effect.

      (Parkhurst and Ish-Horowicz, 1991)

      Postblastoderm cell divisions do take place in homozygous embryos, but at a lower frequency than in wild-type. The length of the cell cycle, in particular the length of the mitotic phase is increased.

      (Hartenstein and Posakony, 1990)

      Mutants show a nonspecific reduction in the number of differentiated cuticular structures.

      (Edgar and O'Farrell, 1989)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      stg1 is an enhancer of visible | recessive phenotype of CycEJP

      (Secombe et al., 1998)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      stg1 is an enhancer of eye phenotype of CycEJP

      (Secombe et al., 1998)
      NOT Enhancer of
      Statement
      Reference

      stg[+]/stg1 is a non-enhancer of mitotic domain 1 | embryonic cycle 14 phenotype of CycB+t10

      (Ji et al., 2002)
      NOT Suppressor of
      Statement
      Reference

      stg[+]/stg1 is a non-suppressor of mitotic domain 1 | embryonic cycle 14 phenotype of CycB+t10

      (Ji et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Dominantly enhances the rough eye phenotype of CycEJP homozygotes.

      (Secombe et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      References (12)