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General Information
Symbol
Dmel\stg6
Species
D. melanogaster
Name
FlyBase ID
FBal0016178
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
stg9A, stg9A19
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

No visible eye defects are seen in heterozygous stg6 mutant flies.

In those embryos that are incubated at the restrictive temperature of 29oC before the division of the ganglion mother cell into RP2/sib, the ganglion mother cell assumes an RP2 identity. In the aCC/pCC lineage, the ganglion mother cell assumes an aCC identity. A 30 minute delay into G2 entry is also found in these embryos.

Cells in homozygous clones induced in the wing pouch of the wing disc divide slowly when maintained at a semi-permissive temperature and become enlarged. These cells are gradually lost from the disc epithelium.

Embryos derived from germ line clones proceed through cycles 1-13 normally.

Postblastoderm cell divisions do take place in homozygous embryos, but at a lower frequency than in wild-type. The length of the cell cycle, in particular the length of the mitotic phase is increased.

Mutants show a nonspecific reduction in the number of differentiated cuticular structures.

weak allele

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

stg6/stg[+] is an enhancer of visible | adult stage | heat sensitive phenotype of Hsap\YWHAGhs.cHa

Phenotype Manifest In
Other
Statement
Reference

Hsap\YWHAGhs.cHa, stg6/stg[+] has eye | heat sensitive phenotype

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

Heterozygous stg6 induces a rough eye phenotype when flies expressing Hsap\YWHAGhs.cHa are heat-shocked at 37[o]C for 30 minutes every 7.5 hours from the third instar stage. 8.96% of flies have a rough eye compared to only 1.61% in the absence of stg6 and 1.39% in wild type controls. No eye defects are seen in heterozygous stg6.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
References (8)