FlyBase Allele Report: Dmel\w[t]

General Information

Symbol

Dmel\w^t

Species

D. melanogaster

Name

tinged

FlyBase ID

FBal0018313

Feature type

allele

Associated gene

Dmel\w

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

spontaneous

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Lloyd et al., 2002)

Mutagen

spontaneous

Progenitor genotype

Cytology

Description

Unknown.

(Birchler and Hiebert, 1989)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal eye color

(Lloyd et al., 2002)

visible | recessive

Phenotype Manifest In

Malpighian tubule

pigment cell

(Lloyd et al., 2002)

Detailed Description

Statement

Reference

Homozygotes have faint pink eyes with only 0.6% red pigment (compared to 100% pigment in wild type).

(Lloyd et al., 2002)

Malpighian tubule colour: colourless. Eye colour: light pinkish.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

w^t/w^e(g) is an enhancer of abnormal eye color phenotype of g²

(Lloyd et al., 2002)

w^t/w^e(g) is an enhancer of abnormal eye color phenotype of g^50e

(Lloyd et al., 2002)

Phenotype Manifest In

Enhanced by

Statement

Reference

w^t has phenotype, enhanceable by Mow^gamma

(Bhadra and Birchler, 1996)

NOT Enhanced by

Statement

Reference

w^t has phenotype, non-enhanceable by In(3)Msu¹

(Csink et al., 1994)

w^t has phenotype, non-enhanceable by In(3)Msu²

(Csink et al., 1994)

w^t has phenotype, non-enhanceable by Rm62^D

(Csink et al., 1994)

w^t has phenotype, non-enhanceable by Rm62^Dem

(Csink et al., 1994)

w^t has phenotype, non-enhanceable by Rm62^E

(Csink et al., 1994)

w^t has phenotype, non-enhanceable by Rm62^F

(Csink et al., 1994)

w^t has phenotype, non-enhanceable by Rm62^H

(Csink et al., 1994)

w^t has phenotype, non-enhanceable by Rm62^K

(Csink et al., 1994)

w^t has phenotype, non-enhanceable by E(w^a)¹

(Birchler and Hiebert, 1989)

NOT suppressed by

Statement

Reference

w^t has phenotype, non-suppressible by In(3)Msu¹

(Csink et al., 1994)

w^t has phenotype, non-suppressible by In(3)Msu²

(Csink et al., 1994)

w^t has phenotype, non-suppressible by Rm62^D

(Csink et al., 1994)

w^t has phenotype, non-suppressible by Rm62^Dem

(Csink et al., 1994)

w^t has phenotype, non-suppressible by Rm62^E

(Csink et al., 1994)

w^t has phenotype, non-suppressible by Rm62^F

(Csink et al., 1994)

w^t has phenotype, non-suppressible by Rm62^H

(Csink et al., 1994)

w^t has phenotype, non-suppressible by Rm62^K

(Csink et al., 1994)

w^t has phenotype, non-suppressible by su(Hw)²

(Lindsley and Grell, 1968)

Enhancer of

Statement

Reference

w^t/w^e(g) is an enhancer of pigment cell phenotype of g²

(Lloyd et al., 2002)

w^t/w^e(g) is an enhancer of pigment cell phenotype of g^50e

(Lloyd et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Male w^t, g^53d double mutant flies have lower levels of pigment in the eye than w^t single mutants, leading to a change in eye colour from faint pink to completely white.

(Lloyd et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (2)

Holtzman, S. and Kaufman, T. (2013)

Mutant

Wild-type

Stocks (2)

Bloomington

166

w^t fw¹

Kyoto

105764

w^t fw¹

Notes on Origin

Discoverer

Hyde, 2nd Nov. 1914.

Comments

Lesion unknown.

(Bhadra and Birchler, 1996)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

w^t

Name Synonyms

tinged

Secondary FlyBase IDs

References (7)

Report Sections

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