FB2026_02 , released June 18, 2026
Allele: Dmel\Adv1
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General Information
Symbol
Dmel\Adv1
Species
D. melanogaster
Name
FlyBase ID
FBal0028921
Feature type
allele
Associated gene
Adv
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Preiss and Artavanis-Tsakonas, 1991)
Progenitor genotype
Caused by aberration
In(2R)Adv
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adv1/+ flies exhibit fusion between L1 and L2 via a bridge of ectopic vein at approximately same proximal-distal position as the anterior cross-vein.

      (Srivastava et al., 2002)

      Mutants show a spur from L1 that runs further than L1 does normally, most apparent at the base of the wing.

      (Heilig, 1995.1.27)

      First longitudinal wing vein split, follows the route of the second vein up to the level of the anterior crossvein where it turns toward the margin, branching twice. Third longitudinal vein is no longer attached to L1. Heterozygote viable.

      (Preiss and Artavanis-Tsakonas, 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Adv1 has wing vein L1 phenotype, enhanceable by bs03267/bs[+]

      (Srivastava et al., 2002)

      Adv1 has wing vein L2 phenotype, enhanceable by bs03267/bs[+]

      (Srivastava et al., 2002)

      Adv1 has wing vein | ectopic phenotype, enhanceable by bs03267/bs[+]

      (Srivastava et al., 2002)

      Adv1 has wing vein L1 phenotype, enhanceable by Egfr[+]/EgfrE1

      (Srivastava et al., 2002)

      Adv1 has wing vein L2 phenotype, enhanceable by Egfr[+]/EgfrE1

      (Srivastava et al., 2002)

      Adv1 has wing vein | ectopic phenotype, enhanceable by Egfr[+]/EgfrE1

      (Srivastava et al., 2002)

      Adv1 has wing vein L1 phenotype, enhanceable by pan[+]/panunspecified

      (Srivastava et al., 2002)

      Adv1 has wing vein L2 phenotype, enhanceable by pan[+]/panunspecified

      (Srivastava et al., 2002)

      Adv1 has wing vein | ectopic phenotype, enhanceable by pan[+]/panunspecified

      (Srivastava et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      bs03267, EgfrE1 and panunspecified all dominantly enhance the 'additional vein' phenotype of Adv1/+ flies.

      (Srivastava et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (6)
      Notes on Origin
      Discoverer
      Comments
      Comments

      While complementation data indicate that the recessive lethality of In(2R)Adv is due to disruption of en, en expression appears normal in heterozygotes, suggesting that the dominant "additional vein" phenotype of this inversion is not due to its effects on en.

      (Srivastava et al., 2002)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Adv1
      Name Synonyms
      Secondary FlyBase IDs
        References (4)