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General Information
Symbol
Dmel\CycBhs.PK
Species
D. melanogaster
Name
heat shock construct of Knoblich
FlyBase ID
FBal0029136
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
hs-cycB
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Expression of CycB cDNA driven from a heat shock promoter.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of CycBhs.PK does not induce S phase. S phase is not induced in embryos when cdc2AF.hs is co-expressed with CycBhs.PK using heat shock.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement
Reference
NOT Suppressor of
Statement
Reference
Other
Additional Comments
Genetic Interactions
Statement
Reference

Coexpression of cdc2AF.hs, CycBhs.PK and CycB3hs.PS does not suppress this phenotype in CycAC8LR1 mutant embryos fails to restore mitosis 16 in the epidermis.

Many cells of heatshocked embryos carrying cdc2AF.hs and CycBhs.PK fail to delay mitosis after irradiation.

Neuroblasts in trolsd larval brains show a proliferation defect. Expression of CycBhs.PK in trolsd larvae using heat shock is unable to rescue this defect; there is no change in the number of S phase neuroblasts in the brain.

Heat induced coexpression of CycBhs.PK and Cdk1AF.hs induces proliferation in quiescent pole cells. Ectopic mitoses are followed by cell division in pole cells.

Rescues mutant phenotype of embryos double mutant for CycA3.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (3)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
CycBhs.PK
Name Synonyms
heat shock construct of Knoblich
Secondary FlyBase IDs
    References (11)