FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\chicneo
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General Information
Symbol
Dmel\chicneo
Species
D. melanogaster
Name
FlyBase ID
FBal0030749
Feature type
allele
Associated gene
Dmel\chic
Associated Insertion(s)
P{hsneo}chicneo
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Cooley et al., 1992)
Progenitor genotype
Associated Insertion(s)
P{hsneo}chicneo
Cytology
Description

Insertion of a P{hsneo} element in the first intron.

(Giansanti et al., 1998)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      No Assay Recorded
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage | female
      (Cooley et al., 1992)
      northern blot
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage | male
      (Cooley et al., 1992)
      Additional Information
      Statement
      Reference

      The 1.0kb chi transcript is absent in chineo flies.

      (Cooley et al., 1992)

      The 1.2kb chi transcript is present in RNA from males and females in chineo flies.

      (Cooley et al., 1992)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      chic11/chicneo females fail to complete nurse cell dumping during oogenesis stage 13 because they are unable to form cytoplasmic actin bundles. This results in larger nurse cells and a smaller oocyte than controls.

      chic11/chicneo nurse cells have normal nucleolar structure.

      (Groen et al., 2015)

      Fully penetrant egg chamber phenotype: nurse cells fail to deliver all their cytoplasm to the oocyte resulting in small oocytes surrounded by an egg shell. Strong allele of chic.

      (Cooley et al., 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      chineo
      chicfs(2)neo1
      (Groen et al., 2015)
      chicfs(2)neo
      (Ogienko et al., 2018)
      chicneo
      fs(2)neo1
      (Beaton, 1999.12.12)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)