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General Information
Symbol
Dmel\nos17
Species
D. melanogaster
Name
FlyBase ID
FBal0032290
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
nosRW
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Nucleotide change:

    G19159254A

    Reported nucleotide change:

    G2020A

    Amino acid change:

    D380N | nos-PA; D361N | nos-PB

    Reported amino acid change:

    D380N

    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference

    Amino acid replacement: D380N. Nucleotide substitution: G2020A.

    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 1 )
    Disease
    Interaction
    References
    ameliorates  brain cancer
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    No genetic interaction in terms of abdominal segmentation and oogenesis is seen in the cupunspecified/+ ; nos17/Df combination.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Suppressor of
    Statement
    Reference

    nos17/Df(3R)Dl-FX1 is a suppressor of neoplasia phenotype of l(3)mbtts1

    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    Comments
    Comments

    Weak allele of nos. Pole plasm is present and functional in germ cell determination. Cytoplasmic transplantation of wild type pole plasm into the abdominal region restores normal abdominal development: surviving adults are fertile.

    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    References (8)