FlyBase Allele Report: Dmel\Syt1[elav.PD]

General Information

Symbol

Dmel\Syt1^elav.PD

Species

D. melanogaster

Name

embryonic lethal, abnormal vision promoter construct of Di Antonio

FlyBase ID

FBal0032855

Feature type

allele

Associated gene

Dmel\Syt1

Associated Insertion(s)

Carried in Construct

P{elav-syt}

Key Links

Transgenic product class

cDNA

(DiAntonio et al., 1993)

wild_type

(DiAntonio et al., 1993)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(DiAntonio et al., 1993)

wild_type

(DiAntonio et al., 1993)

Mutagen

in vitro construct

(DiAntonio et al., 1993)

Progenitor genotype

Carried in construct

P{elav-syt}

Cytology

Description

Syt1 cDNA expressed from elav promoter.

(DiAntonio et al., 1993)

Allele components

Component

Use(s)

Regulatory region(s)

elav

Encoded product / tool

Syt1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal behavior

(DiAntonio et al., 1993)

wild-type

(Phillips et al., 2000, DiAntonio and Schwarz, 1994)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Syt1^D27/Syt1^AD4, Syt1^elav.PD, stnA¹⁵, stnB¹⁵ has viable phenotype

(Phillips et al., 2000)

Syt1^D27/Syt1^AD4, Syt1^elav.PD, stnA⁶ has lethal phenotype

(Phillips et al., 2000)

Syt1^D27/Syt1^AD4, Syt1^elav.PD, stnA⁶ has uncoordinated phenotype

(Phillips et al., 2000)

Syt1^D27/Syt1^AD4, Syt1^elav.PD, stnA⁷ has lethal phenotype

(Phillips et al., 2000)

Syt1^D27/Syt1^AD4, Syt1^elav.PD, stnA⁷ has uncoordinated phenotype

(Phillips et al., 2000)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Syt1^elav.PD rescues Syt1^D27/Syt1^AD4

(Phillips et al., 2000)

Syt1^elav.PD rescues Df(2L)DTD2/Syt1^AD1

(DiAntonio and Schwarz, 1994)

Partially rescues

Syt1^elav.PD partially rescues Syt1^AD1

(DiAntonio and Schwarz, 1994)

Syt1^elav.PD partially rescues Syt1^AD3

(DiAntonio and Schwarz, 1994)

Syt1^elav.PD partially rescues Syt1^AD4

(DiAntonio and Schwarz, 1994)

Syt1^elav.PD partially rescues Syt1^D27

(DiAntonio and Schwarz, 1994)

Syt1^elav.PD partially rescues Syt1^D27

(DiAntonio et al., 1993)

Syt1^elav.PD partially rescues Syt1^unspecified

(DiAntonio et al., 1993)

Comments

Rescues the lethality of syt^AD4/syt^D27.

(Phillips et al., 2000)

syt^AD1/Df(2L)DTD2; P{elav-syt}/+ individuals are more robust than the rescued null alleles: they fly more and climb up the sides of the vial more quickly after being tapped to the bottom.

(DiAntonio and Schwarz, 1994)

Rescues lethality of syt^D27 and ethyl methanesulfonate-induced syt alleles. Rescued flies are not completely wild type, showing sluggish, uncoordinated walking behaviour and flightlessness.

(DiAntonio et al., 1993)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Rescue syt mutants in trans to syt^N6.

(Littleton et al., 1994)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Syt1^elav.PD

syt^elav.PD

Name Synonyms

embryonic lethal, abnormal vision promoter construct of Di Antonio

Secondary FlyBase IDs

References (4)

Report Sections

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