FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CycEunspecified
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General Information
Symbol
Dmel\CycEunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0033574
Feature type
allele
Associated gene
Dmel\CycE
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Adult escapers have small eyes.

        (Ashburner et al., 1990)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        NOT Enhancer of
        Statement
        Reference

        CycEunspecified is a non-enhancer of visible phenotype of Wee1GMR.PP

        (Price et al., 2002)

        CycEunspecified is a non-enhancer of visible phenotype of Myt1GMR.PP

        (Price et al., 2002)
        Suppressor of
        Statement
        Reference

        CycE[+]/CycEunspecified is a suppressor of abnormal mitotic cell cycle phenotype of encunspecified

        (Ohlmeyer and Schupbach, 2003)
        NOT Suppressor of
        Statement
        Reference

        CycEunspecified is a non-suppressor of visible phenotype of Myt1GMR.PP

        (Price et al., 2002)

        CycEunspecified is a non-suppressor of visible phenotype of Wee1GMR.PP

        (Price et al., 2002)
        Other
        Statement
        Reference

        Cdk43, CycEunspecified has lethal | recessive phenotype

        (Meyer et al., 2000)
        Phenotype Manifest In
        NOT Enhancer of
        Statement
        Reference

        CycEunspecified is a non-enhancer of eye phenotype of Wee1GMR.PP

        (Price et al., 2002)

        CycEunspecified is a non-enhancer of eye phenotype of Myt1GMR.PP

        (Price et al., 2002)
        Suppressor of
        Statement
        Reference

        CycE[+]/CycEunspecified is a suppressor of egg chamber phenotype of encunspecified

        (Ohlmeyer and Schupbach, 2003)
        NOT Suppressor of
        Statement
        Reference

        CycE[+]/CycEunspecified is a non-suppressor of egg chamber phenotype of twinry3

        (Morris et al., 2005)

        CycEunspecified is a non-suppressor of eye phenotype of Myt1GMR.PP

        (Price et al., 2002)

        CycEunspecified is a non-suppressor of eye phenotype of Wee1GMR.PP

        (Price et al., 2002)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The frequency of the degrading egg chamber phenotype seen in twinry3 hemizygotes is not significantly altered by CycEunspecified/+.

        (Morris et al., 2005)

        The extra mitotic division phenotype seen in the egg chambers of encunspecified females at 29oC is suppressed from 70% to 10% by CycEunspecified/+.

        (Ohlmeyer and Schupbach, 2003)

        Expression of dltdsRNA.Scer\UAS in a CycEunspecified heterozygous mutant background causes only a very moderate decrease in the number of wing cells.

        (Pielage et al., 2003)

        Heterozygosity in CycEunspecified is tolerated in Cdk43 heterozygotes, but leads to complete lethality in Cdk43 homozygotes.

        (Meyer et al., 2000)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        CycEunspecified
        unspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (9)