FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\MetK17
Open Close
General Information
Symbol
Dmel\MetK17
Species
D. melanogaster
Name
FlyBase ID
FBal0033993
Feature type
allele
Associated gene
Dmel\Met
Associated Insertion(s)
P{}MetK17
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Wilson, 1996)
Mutagen
P-element activity
(Wilson, 1996)
Progenitor genotype
Associated Insertion(s)
P{}MetK17
Cytology
Description

P-element insertion within 5' untranslated sequences, 424bp from the start of the open reading frame.

(Ashok et al., 1998)

Insertion of a P-element.

(Wilson, 1996)

Insertion of a complete 2.9kb P-element.

(Turner and Wilson, 1995)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant males do not show genital rotation defects.

      (Adam et al., 2003)

      Heterozygous larvae show increased resistance to Methoprene compared to wild-type.

      (Wilson, 1996)

      Flies are methoprene-resistant.

      (Turner and Wilson, 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      MetK17 is a suppressor of visible phenotype of Fas2spin

      (Adam et al., 2003)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      MetK17 is a suppressor of male genitalia phenotype of Fas2spin

      (Adam et al., 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The genital rotation defects seen in Fas2spin males are completely suppressed by Rst(1)JHK17.

      (Adam et al., 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      Tom Wilson.

      Comments
      Comments

      Mutation is revertable to wild type (methoprene-susceptible) at high frequency.

      (Turner and Wilson, 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      MetK17
      (Adam et al., 2003, Ashok et al., 1998, Wilson, 1996, Turner and Wilson, 1995)
      Rst(1)JHK17
      Name Synonyms
      Secondary FlyBase IDs
        References (4)