FB2026_02 , released June 18, 2026
Allele: Dmel\ctp1
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General Information
Symbol
Dmel\ctp1
Species
D. melanogaster
Name
FlyBase ID
FBal0034380
Feature type
allele
Associated gene
Dmel\ctp
Associated Insertion(s)
P{lacW}ctp1
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Phillis et al., 1996)
Mutagen
P-element activity
(Phillis et al., 1996, Gramates and Phillis, 1995, Phillis et al., 1994)
Progenitor genotype
Associated Insertion(s)
P{lacW}ctp1
Cytology
Description

P{lacW} insertion is within 1kb of the transcribed region.

(Phillis et al., 1996)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      head & macrochaeta

      (Phillis et al., 1996)

      macrochaeta

      (Phillis et al., 1994)

      scutum & macrochaeta

      (Phillis et al., 1996)

      scutum & microchaeta

      (Phillis et al., 1996)
      Detailed Description
      Statement
      Reference

      Mild defects in grooming behaviour. Also subtle changes in the external structure of sensory receptors; producing thinner and shorter macrochaetae on notum and head, occasional loss of notal macrochaetae and mild reduction in the number of notal microchaetae. ctp1/ctpe73 and ctp1/Df(1)RC40 transheterozygotes are semi-viable and exhibit the same macro- and microchaetae embryonic phenotype as the homozygote.

      (Phillis et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      ctp1 is an enhancer of phenotype of ctunspecified

      (Gramates and Phillis, 1995)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Enhances the phenotype of alleles of the Lethal I class of ct mutations.

      (Gramates and Phillis, 1995)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Excision alleles have been generated, several are lethal, others show gross defects in bristles and the ocelli.

      (Phillis et al., 1994)

      ctp1 interacts with genes of the ac-sc complex and has a non-additive interaction with eppy.

      (Gramates and Phillis, 1995)

      Excision of the P{lacW} insertion recovered lethal alleles, viable alleles with mutant bristle phenotypes and wild-type revertants.

      (Phillis et al., 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ctp1
      ctpE4
      Name Synonyms
      Secondary FlyBase IDs
        References (3)