FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ndlrm5
Open Close
General Information
Symbol
Dmel\ndlrm5
Species
D. melanogaster
Name
FlyBase ID
FBal0035254
Feature type
allele
Associated gene
Dmel\ndl
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
    Nature of the Allele
    Allele class

    loss of function allele

    (LeMosy and Hashimoto, 2000)
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Nucleotide substitution: G4346A. Amino acid replacement: A1360T. Mutation is within the catalytic domain.

    (LeMosy et al., 2000)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    3L:6,598,305..6,598,305 [-]
    Nucleotide change:

    G6598305A

    Reported nucleotide change:

    G4346A

    Amino acid change:

    A1360T | ndl-PA

    Reported amino acid change:

    A1360T

    Comment:

    Position of mutation on reference sequence inferred by FlyBase curator based on author statement.

    (LeMosy et al., 2000)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Allele is inactive in dorsoventral polarity establishment.

        (LeMosy et al., 2000)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments

        Shows dominant negative inhibition of ndl9.

        (LeMosy et al., 2000)
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        Comments
        Comments

        Class II allele.

        (LeMosy et al., 2000)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        mel(3)5
        (Anderson and Nusslein-Volhard, 1984)
        ndlRM5
        (LeMosy and Hashimoto, 2000, LeMosy et al., 2000)
        ndlrm5
        (Alpar et al., 2018)
        Name Synonyms
        Secondary FlyBase IDs
        • FBal0103638
        References (5)